Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, 1-100, Kusumoto-cho, Chikusa-ku, Nagoya, 464-8650, Japan.
J Dent Res. 2011 Feb;90(2):199-202. doi: 10.1177/0022034510382548.
Numerous cross-sectional epidemiological studies suggest that obesity is associated with periodontal disease. This longitudinal study tested whether body mass index (BMI) was related to the development of periodontal disease in a sample of employed Japanese participants. Data are from the statutory medical checkups routinely collected for employees in and around Nagoya, Japan. The authors tested the relationship between BMI at baseline and the 5-year incidence of periodontal disease in a sample of 2787 males and 803 females. The hazard ratios for developing periodontal disease after 5 years were 1.30 (P < .001) and 1.44 (P = .072) in men and 1.70 (P < .01) and 3.24 (P < .05) in women for those with BMIs of 25-30 and ≥ 30, respectively, compared to those with BMI < 22, after adjusting for age, smoking status, and clinical history of diabetes mellitus. These findings demonstrate a dose-response relationship between BMI and the development of periodontal disease in a population of Japanese individuals.
许多横断面流行病学研究表明,肥胖与牙周病有关。这项纵向研究检验了在日本名古屋及其周边地区的在职员工样本中,体重指数(BMI)是否与牙周病的发展有关。数据来自日本法定体检,是为员工定期收集的。作者在 2787 名男性和 803 名女性样本中检验了基线 BMI 与 5 年内牙周病发病的关系。与 BMI<22 的人相比,BMI 为 25-30 和≥30 的男性和女性发生牙周病的风险比分别为 1.30(P<.001)和 1.44(P=.072)以及 1.70(P<.01)和 3.24(P<.05),调整年龄、吸烟状况和糖尿病临床史后。这些发现表明,在日本人群中,BMI 与牙周病的发展之间存在剂量反应关系。