School of Population Health, University of Auckland, Auckland, New Zealand.
Appl Health Econ Health Policy. 2011 Mar 1;9(2):111-23. doi: 10.2165/11531500-000000000-00000.
Osteoporosis is recognized as a serious health condition in developed as well as developing countries. There are no accurate estimates of the extent of the burden of osteoporosis in New Zealand. The purpose of this study was to estimate the economic burden of osteoporosis in New Zealand using data from international studies and population and health services information from New Zealand.
To estimate the number of osteoporotic fractures and cost of treatment and management of osteoporosis and osteoporotic fractures to the health system in New Zealand in 2007 and to project the future burden in 2013 and 2020.
Hospitalizations for hip fractures were combined with New Zealand census data and estimates from previous studies to estimate the expected number of osteoporotic vertebral, humeral, pelvic and other sites fractures in 2007. Health services usage and costs were estimated by combining data from New Zealand hospitals, the New Zealand Health Survey on the number of people diagnosed with osteoporosis, and the New Zealand Health Information Service (NZHIS) on pharmaceutical treatments. All prices are in New Zealand dollars ($NZ), year 2007 values. Losses in QALYs resulting from osteoporotic fractures were used to indicate the impact on morbidity and mortality. The lost QALYs and economic cost associated with osteoporosis were projected to 2013 and 2020 using population projections from the New Zealand census.
There were an estimated 84 354 osteoporotic fractures in New Zealand in 2007, including 3803 hip and 27 994 vertebral fractures. Osteoporosis resulted in a loss of 11 249 QALYs. The total direct cost of osteoporosis was$NZ330 million, including $NZ212 million to treat the fractures, $NZ85 million for care after fractures and $NZ34 million for treatment and management of the estimated 70 631 people diagnosed with osteoporosis. Sensitivity analysis suggested the results were robust to assumptions regarding the number of fractures receiving medical treatment. Hospitalization costs represented a significant component of total costs. The cost of treatment and management of osteoporosis is expected to increase to over $NZ391 million in 2013 and $NZ458 million in 2020, with the number of QALYs lost increasing to 13 205 in 2013 and 15 176 in 2020.
Osteoporosis and osteoporotic fractures create a significant burden on the health system in New Zealand. This study highlights the significant scope of the burden of osteoporosis and the potential gains that might be made from introducing interventions to mitigate the burden.
骨质疏松症在发达国家和发展中国家都是一个严重的健康问题。新西兰骨质疏松症的负担程度尚无准确估计。本研究的目的是利用国际研究数据和新西兰人口及卫生服务信息,估算新西兰骨质疏松症的经济负担。
估算 2007 年新西兰卫生系统治疗和管理骨质疏松症及骨质疏松性骨折的费用,预测 2013 年和 2020 年的未来负担。
将髋部骨折住院人数与新西兰人口普查数据和以往研究的估计数结合起来,估算 2007 年预计的骨质疏松性椎体、肱骨、骨盆和其他部位骨折数。将新西兰医院、新西兰骨质疏松症健康调查(调查诊断骨质疏松症人数)和新西兰健康信息服务(NZHIS)的药物治疗数据结合起来,估算卫生服务的使用和费用。所有价格均为新西兰元($NZ),2007 年的数值。骨质疏松性骨折导致的 QALYs 损失用于表明对发病率和死亡率的影响。利用新西兰人口普查的人口预测,将与骨质疏松症相关的 QALY 损失和经济成本预测至 2013 年和 2020 年。
2007 年新西兰有 84354 例骨质疏松性骨折,包括 3803 例髋部骨折和 27994 例椎体骨折。骨质疏松症导致 11249 个 QALY 损失。骨质疏松症的直接总成本为 3.30 亿新西兰元,其中 2.12 亿新西兰元用于治疗骨折,8500 万新西兰元用于骨折后护理,3400 万新西兰元用于治疗和管理估计的 70631 名骨质疏松症患者。敏感性分析表明,对于接受治疗的骨折数量的假设,结果是稳健的。住院费用占总费用的很大一部分。2013 年治疗和管理骨质疏松症的费用预计将增加到 3.91 亿新西兰元以上,2020 年将增加到 4.58 亿新西兰元以上,2013 年损失的 QALY 将增加到 13205 个,2020 年将增加到 15176 个。
骨质疏松症和骨质疏松性骨折给新西兰卫生系统带来了巨大负担。本研究强调了骨质疏松症负担的显著范围,以及通过引入干预措施减轻负担可能带来的巨大收益。