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营养与饮食模式与绝经后骨质疏松症发病机制的关系——文献综述

Nutrient and Dietary Patterns in Relation to the Pathogenesis of Postmenopausal Osteoporosis-A Literature Review.

作者信息

Ilesanmi-Oyelere Bolaji Lilian, Kruger Marlena C

机构信息

School of Health Sciences, College of Health, Massey University, Tennent Drive, Palmerston North 4442, New Zealand.

Riddet Institute, Massey University, Palmerston North 4442, New Zealand.

出版信息

Life (Basel). 2020 Sep 25;10(10):220. doi: 10.3390/life10100220.

Abstract

Postmenopausal women tend to be susceptible to primary osteoporosis due to its association with oestrogen deficiency. There is emerging evidence that an unhealthy dietary pattern drives an increase in the risk of postmenopausal osteoporosis (PO), whereas a healthy dietary pattern may decrease its occurrence. In this narrative literature review, we sought to review the role of nutrient and dietary patterns in the pathogenesis of PO. Therefore, we searched and reported all research articles from 2001 to May 2020 in Web of Science, Cinahl and Scopus that have researched a relationship between nutrient and/or dietary patterns and postmenopausal osteoporosis. Nutrients such as calcium, phosphorus, magnesium and vitamin D have been proven to be beneficial for bone health. Meanwhile, for the dietary patterns, foods such as dairy products especially milk, fibre and protein-rich foods, e.g., meat were directly linked to a positive association with bone mineral density (BMD). Likewise, fruits, vegetables and probiotic and prebiotic foods were reported for its positive relationship with BMD. Therefore, aside from physical activity, nutrition and diet in adequate proportions are suggested to be an important tool for ameliorating osteoporosis and bone health issues in older age.

摘要

绝经后女性由于与雌激素缺乏相关,往往易患原发性骨质疏松症。越来越多的证据表明,不健康的饮食模式会增加绝经后骨质疏松症(PO)的风险,而健康的饮食模式可能会降低其发生率。在这篇叙述性文献综述中,我们试图探讨营养素和饮食模式在PO发病机制中的作用。因此,我们检索并报告了2001年至2020年5月在Web of Science、Cinahl和Scopus中所有研究营养素和/或饮食模式与绝经后骨质疏松症之间关系的研究文章。钙、磷、镁和维生素D等营养素已被证明对骨骼健康有益。同时,对于饮食模式,乳制品尤其是牛奶、富含纤维和蛋白质的食物(如肉类)等食物与骨矿物质密度(BMD)呈正相关。同样,水果、蔬菜以及益生菌和益生元食物也被报道与BMD呈正相关。因此,除了体育活动外,适当比例的营养和饮食被认为是改善老年人骨质疏松症和骨骼健康问题的重要手段。

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