使用列线图和脉搏波速度指数对固有动脉僵硬进行个体评估：大盐研究。

Individual assessment of inherent arterial stiffness using nomogram and pulse wave velocity index: the Ohasama study.

机构信息

Department of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Medicine, Sendai, Japan.

出版信息

Clin Exp Hypertens. 2011;33(3):147-52. doi: 10.3109/10641963.2010.531839. Epub 2011 Jan 27.

DOI:10.3109/10641963.2010.531839

PMID:21271815

Abstract

We measured the brachial-ankle pulse wave velocity (baPWV) in 491 normotensives and determined the "PWV index" (measured baPWV-theoretical baPWV) in 491 normotensives and 83 controlled hypertensives. Linear regression analysis revealed that the theoretical baPWV (cm/sec) was 0.21 × age(2) (years(2))-13.73 × age (years) + 0.05 × mean arterial pressure(2) (mmHg(2)) + 3.95 × heart rate (bpm) + 36.49 × gender (1 male; 0 female) + 733 (R(2) = 0.53). The calculated PWV index was significantly higher in 13 smokers than 70 nonsmokers among controlled hypertensives. The calculated PWV index might provide more precise information about inherent arterial stiffness.

摘要

我们在 491 名血压正常者中测量了肱踝脉搏波速度（baPWV），并在 491 名血压正常者和 83 名控制型高血压患者中确定了“PWV 指数”（实测 baPWV-理论 baPWV）。线性回归分析显示，理论 baPWV（cm/sec）为 0.21×年龄 2（岁 2）-13.73×年龄（岁）+0.05×平均动脉压 2（mmHg 2）+3.95×心率（bpm）+36.49×性别（1 为男性；0 为女性）+733（R 2=0.53）。在控制型高血压患者中，13 名吸烟者的计算 PWV 指数明显高于 70 名不吸烟者。计算的 PWV 指数可能提供更准确的有关固有动脉僵硬的信息。