Reinig Erica F, Albertson Dan, Sarma Deba
Department of Pathology, Creighton University Medical Center, Omaha, Nebraska, USA.
Dermatol Online J. 2011 Jan 15;17(1):12.
Sarcoptes scabiei is an obligate ectoparasite, which burrows into the stratum granulosum of the epidermis and lays its eggs. The resultant host inflammatory response leads to intensely pruritic papules.
A 63-year-old man undergoing treatment for immunoproliferative disease was suspected of having a pruritic drug eruption. Subsequent skin biopsy revealed an intracorneal burrow containing three pink, refractile pigtail-like structures, believed to be empty eggshells of S. scabiei.
Traditionally, the presence of adult mites or eggs in skin scrapings or a skin biopsy is required for a definitive diagnosis of scabies. However, our case and similar cases suggest that the diagnosis of scabies can also be made on the basis of pink pigtail-like structures, remnants of eggshells, within the intracorneal burrow.
疥螨是一种专性体外寄生虫,它钻入表皮颗粒层并产卵。由此产生的宿主炎症反应导致剧烈瘙痒的丘疹。
一名正在接受免疫增殖性疾病治疗的63岁男性被怀疑患有瘙痒性药疹。随后的皮肤活检显示角质层内有一个洞穴,其中含有三个粉红色、有折光性的猪尾状结构,据信是疥螨的空蛋壳。
传统上,确诊疥疮需要在皮肤刮片或皮肤活检中发现成年螨虫或虫卵。然而,我们的病例及类似病例表明,疥疮的诊断也可基于角质层内洞穴中粉红色猪尾状结构(蛋壳残余物)做出。