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围手术期心肌梗死后冠状动脉移植血管通畅情况:一项多层螺旋计算机断层扫描研究

Coronary graft patency after perioperative myocardial infarction: a study with multislice computed tomography.

作者信息

Bassiri Hosseinali, Nematollahi Alireza, Noohi Fereidoun, Hashemi Jafar, Motevali Marzieh, Givtaj Nader, Raissi Kamal, Haghjoo Majid

机构信息

Department of Interventional Cardiology, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Interact Cardiovasc Thorac Surg. 2011 Apr;12(4):596-9. doi: 10.1510/icvts.2010.261834. Epub 2011 Jan 27.

Abstract

A total of 55 consecutive patients who experienced perioperative myocardial infarction (MI) after coronary artery bypass grafting were studied using multislice computed tomography (MSCT) angiography to evaluate for graft patency. The MSCT detected acute graft occlusion in 23% grafts. Of the 55 patients, 40% patients had occluded grafts and perioperative MI in the area of the grafted vessels; remaining 60% had patent grafts with infarction in the area of the grafted vessels. Compared with the patients with patent grafts, those with occluded grafts had a higher blood sugar level. In addition, graft occlusion was higher in grafts with severe distal disease. Among the patients with patent grafts, luminal stenosis of the native vessels supplying the infarcted myocardium was higher than that in the native vessels supplying the non-infarcted myocardium. In conclusion, MSCT is feasible for the assessment of graft patency in the setting of perioperative MI. Graft occlusion is detected in less than half of the cases and usually occurs in the grafts with severe distal involvement and the patients with uncontrolled hyperglycemia. In patients with patent grafts, the severity of luminal stenosis of the native grafted vessel is the main predisposing factor for perioperative MI.

摘要

共对55例冠状动脉搭桥术后发生围手术期心肌梗死(MI)的连续患者进行了研究,采用多层螺旋计算机断层扫描(MSCT)血管造影评估移植血管通畅情况。MSCT检测到23%的移植血管急性闭塞。在这55例患者中,40%的患者移植血管闭塞且移植血管区域发生围手术期心肌梗死;其余60%的患者移植血管通畅,但移植血管区域发生梗死。与移植血管通畅的患者相比,移植血管闭塞的患者血糖水平更高。此外,远端病变严重的移植血管闭塞率更高。在移植血管通畅的患者中,供应梗死心肌的自身血管管腔狭窄程度高于供应未梗死心肌的自身血管。总之,MSCT对于评估围手术期心肌梗死情况下的移植血管通畅情况是可行的。不到一半的病例检测到移植血管闭塞,且通常发生在远端受累严重的移植血管以及血糖控制不佳的患者中。在移植血管通畅的患者中,自身移植血管管腔狭窄的严重程度是围手术期心肌梗死的主要诱发因素。

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