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早产儿和足月儿的收缩期右心室功能:258 例患者三尖瓣环平面收缩期位移(TAPSE)的参考值及 Z 评分值的计算。

Systolic right ventricular function in preterm and term neonates: reference values of the tricuspid annular plane systolic excursion (TAPSE) in 258 patients and calculation of Z-score values.

机构信息

Division of Pediatric Cardiology, Medical University Graz, Graz, Austria.

出版信息

Neonatology. 2011;100(1):85-92. doi: 10.1159/000322006. Epub 2011 Jan 26.

DOI:10.1159/000322006
PMID:21273793
Abstract

BACKGROUND

The tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measurement to assess right ventricular systolic function in adults and children.

OBJECTIVE

We determined growth- and birth weight-related changes of TAPSE to establish reference values in preterm and term neonates.

METHODS

A prospective study was conducted in a group of 258 preterm and term neonates (age: 25+0 to 40+6 weeks of gestation, birth weight: 530-4200 g).

RESULTS

The TAPSE ranged from a mean of 0.44 cm (Z-score ±2: 0.30-0.59 cm) in preterm neonates in the 26th week of gestation to 1.03 cm (Z-score ±2: 0.85-1.21 cm) in term neonates in the 41st week of gestation. The TAPSE values increased in a linear way from the 26th to 41st week of gestation. TAPSE, week of gestation and weight are strongly correlated: Pearson's correlation coefficient was 0.93 for week of gestation - TAPSE (p < 0.001), 0.93 for week of gestation - birth weight (p < 0.001), and 0.89 for birth weight - TAPSE (p < 0.001). There was no statistically significant difference of normal TAPSE values between female and male patients (p = 0.987).

CONCLUSION

Z-scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in preterm and term neonates with structurally normal hearts and with congenital heart disease in the future.

摘要

背景

三尖瓣环平面收缩期位移(TAPSE)是一种评估成人和儿童右心室收缩功能的超声心动图测量方法。

目的

我们确定了 TAPSE 与生长和出生体重的相关变化,以建立早产儿和足月儿的参考值。

方法

对 258 例早产儿和足月儿(胎龄:25+0 至 40+6 周,出生体重:530-4200 克)进行前瞻性研究。

结果

TAPSE 范围从 26 周早产儿的平均 0.44 厘米(Z 评分±2:0.30-0.59 厘米)到 41 周足月儿的 1.03 厘米(Z 评分±2:0.85-1.21 厘米)。TAPSE 值从 26 周到 41 周以线性方式增加。TAPSE、胎龄和体重之间具有很强的相关性:胎龄与 TAPSE 的 Pearson 相关系数为 0.93(p < 0.001),胎龄与出生体重的 Pearson 相关系数为 0.93(p < 0.001),出生体重与 TAPSE 的 Pearson 相关系数为 0.89(p < 0.001)。正常 TAPSE 值在女性和男性患者之间无统计学差异(p = 0.987)。

结论

计算了 TAPSE 值的 Z 分数,并建立了百分位数图表,以便在未来为结构正常的心脏和患有先天性心脏病的早产儿和足月儿提供参考数据。

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