Can Fam Physician. 1985 May;31:1033-7.
Congenital anomalies account for a substantial proportion of childhood morbidity and mortality. They have become proportionately larger because of the decline of such other categories as infections or birth trauma. Approximately 3% of newborns have a serious handicapping or potentially lethal condition; in longterm studies the frequency is much higher. There is no good evidence to suggest that the rates of congenital anomalies are increasing, although this is a common perception. This article discusses diagnosis and management (especially genetic implications) of heart defects, neural tube defects, orofacial clefting, dislocated hip, clubfoot, and hypospadias.
先天性畸形在儿童发病率和死亡率中占很大比例。由于感染或分娩创伤等其他类别病例的减少,其比例变得更大。大约 3%的新生儿有严重的致残或潜在致命的情况;在长期研究中,这一频率要高得多。没有很好的证据表明先天性畸形的发病率正在增加,尽管这是一种常见的看法。本文讨论了心脏缺陷、神经管缺陷、唇腭裂、髋关节脱位、马蹄足和尿道下裂的诊断和治疗(特别是遗传影响)。