A case of erythema multiforme associated with primary Epstein-Barr virus infection.

作者信息

Nakai Hidetaka, Sugata Ken, Usui Chie, Asano Yoshizo, Yamakita Takashi, Matsunaga Kayoko, Mizokuchi Yoshikazu, Katano Harutaka, Iwatsuki Keiji, Yoshikawa Tetsushi

机构信息

Department of Pediatrics, Fujita Health University School of Medicine, Aichi, Japan.

出版信息

Pediatr Dermatol. 2011 Jan-Feb;28(1):23-5. doi: 10.1111/j.1525-1470.2010.01217.x.

DOI:10.1111/j.1525-1470.2010.01217.x

PMID:21276049

Abstract

We present a case of primary Epstein-Barr virus (EBV) infection with erythema multiforme. A 1-year-old Japanese boy presented with skin eruptions, including typical target lesions and a low-grade fever. Just before the skin biopsy, 95 copies/μg DNA of EBV genome was detected in peripheral blood mononuclear cells, which subsequently increased to 6,834 copies/μg DNA. Skin tissue collected from the skin lesion showed the typical pathologic findings of erythema multiforme. EBV-encoded small nuclear RNA signals were not detected in the skin tissue by in situ hybridization.

摘要