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硬膜穿刺后可逆性后部脑病综合征

Post-dural puncture posterior reversible encephalopathy syndrome.

作者信息

Minai Fauzia N, Hasan Syeda Fauzia, Sheerani Mughis

机构信息

Department of Anaesthesia, The Aga Khan University, Karachi.

出版信息

J Coll Physicians Surg Pak. 2011 Jan;21(1):37-9.

PMID:21276384
Abstract

We report the case of a young patient with 36 weeks pregnancy, and an acute respiratory infection with severe bronchospasm, who developed an occipital headache and neck pain on the third day of inadvertent dural puncture during placement of combined epidural spinal anaesthesia for caesarian section. It was diagnosed as post-dural puncture headache until generalised tonic clonic seizures occurred the next day raising the suspicion of postpartum eclampsia or meningitis. Posterior reversible encephalopathy syndrome was diagnosed on MRI of the brain which showed features of reversible ischemia in the posterior region of the brain. With anticonvulsant therapy and antibiotics there was complete resolution of neurological symptoms. We highlight the importance of high index of suspicion of this reversible encephalopathy in obstetric cases with intentional or inadvertent dural puncture, with headache similar to post-dural punctural headache, and the essential role of neuroradiology in confirmation of the diagnosis, as placement of an epidural blood patch would be highly detrimental in these cases.

摘要

我们报告了一例36周妊娠的年轻患者,其患有急性呼吸道感染并伴有严重支气管痉挛,在剖宫产联合硬膜外脊髓麻醉置管时意外发生硬膜穿刺,第三天出现枕部头痛和颈部疼痛。在诊断为硬膜穿刺后头痛后,第二天患者出现全身性强直阵挛发作,这引发了产后子痫或脑膜炎的怀疑。脑部MRI诊断为后部可逆性脑病综合征,显示脑部后部存在可逆性缺血特征。经过抗惊厥治疗和抗生素治疗,神经症状完全缓解。我们强调,对于产科中有意或无意硬膜穿刺且伴有类似硬膜穿刺后头痛的头痛情况,高度怀疑这种可逆性脑病至关重要,同时神经放射学在确诊中起着关键作用,因为在这些病例中放置硬膜外血补丁可能会造成极大损害。

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Posterior reversible encephalopathy syndrome in a child, following splenectomy under combined general and spinal anaesthesia.一名儿童在全身麻醉和脊髓麻醉联合下进行脾切除术后出现后部可逆性脑病综合征。
Anaesth Rep. 2023 Sep 25;11(2):e12245. doi: 10.1002/anr3.12245. eCollection 2023 Jul-Dec.
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Cerebrospinal Fluid Hypovolemia and Posterior Reversible Encephalopathy Syndrome.
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Front Neurol. 2020 Jun 23;11:591. doi: 10.3389/fneur.2020.00591. eCollection 2020.
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Rapid intracranial pressure drop as a cause for posterior reversible encephalopathy syndrome: Two case reports.快速颅内压下降作为后部可逆性脑病综合征的一个病因:两例报告。
Surg Neurol Int. 2017 Jun 5;8:103. doi: 10.4103/sni.sni_55_17. eCollection 2017.
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Reversible cerebral vasoconstriction syndrome and posterior reversible encephalopathy syndrome associated with intracranial hypotension.与颅内低压相关的可逆性脑血管收缩综合征和后部可逆性脑病综合征。
Neurocrit Care. 2017 Feb;26(1):103-108. doi: 10.1007/s12028-016-0320-4.
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