新合成的氨基氧化物和季铵盐的抗菌活性。
Antibacterial activity of new synthesized amino-oxides and quaternary ammonium salts.
作者信息
Cupková V, Espersen F, Høiby N
机构信息
Department of Biochemistry and Microbiology, Faculty of Pharmacy, Comenius University, Czechoslovakia.
出版信息
Zentralbl Hyg Umweltmed. 1990 Oct;190(4):404-11.
PMID:2127889
Abstract
An amino oxide and three quaternary ammonium salts were investigated for antimicrobial activity. All compounds had low MIC against gram positive bacteria. Despite high MIC the ammonium salts gave good killing of Pseudomonas aeruginosa in time kill experiments. These quaternary ammonium salts may be useful for disinfection as they are easily broken down in the environment.
摘要
研究了一种氨基氧化物和三种季铵盐的抗菌活性。所有化合物对革兰氏阳性菌的最低抑菌浓度（MIC）都很低。尽管季铵盐的最低抑菌浓度较高，但在时间杀菌实验中对铜绿假单胞菌有良好的杀灭效果。这些季铵盐在环境中易于分解，可能可用于消毒。
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