Can Fam Physician. 1984 Jul;30:1499-502.
Multiple sclerosis is a common cause of many neurological complaints and disabilities among young, adult Canadians. In the absence of a reliable and specific laboratory test for the disease, the diagnosis is established primarily by clinical criteria, which are outlined in this article. Recent advances in immunology, neurophysiology and neuroimaging have provided techniques to improve diagnostic confidence, particularly in early or atypical cases.
多发性硬化症是导致加拿大年轻成年人群中出现多种神经疾病和残疾的常见病因。由于目前尚无可靠和特异的疾病实验室检测手段,因此主要依据临床标准进行诊断,本文对此进行了概述。近年来免疫学、神经生理学和神经影像学方面的进展提供了一些有助于提高诊断可信度的技术,特别是在早期或非典型病例中。