Kukita J, Yamashita H, Minami T, Fujita I, Koyanagi T, Ueda K
Department of Pediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Acta Paediatr Jpn. 1990 Dec;32(6):625-32. doi: 10.1111/j.1442-200x.1990.tb00896.x.
Between 1980 and 1987, we investigated the outcome for 20 infants with birth weights less than 750 g, admitted to the neonatal unit of Kyushu University Hospital. All infants were delivered at the hospital. Seven infants (35%) survived and were discharged. Comparing the first and second 4 year periods, the survival rate improved from 17% (1 of 6 infants) to 43% (6 of 14 infants). Intensive perinatal care, prevention of infection and early transport of mothers of high-risk babies improved the outcome. In the long-term, among the 7 survivors, 1 had psychomotor retardation, 1 had epilepsy and the other 5 were normal neurologically. Growth in height and weight of these children remained below the -2SD levels until 2 years of age, thereafter they began to catch up. Growth in head circumference increased to a level above the -2SD value from 2 years of age. With intensive perinatal care, the outcome for infants weighting less than 750 g is improving, and good results may be expected.
1980年至1987年间，我们对九州大学医院新生儿病房收治的20名出生体重低于750克的婴儿的预后情况进行了调查。所有婴儿均在该医院分娩。7名婴儿（35%）存活并出院。比较第一个和第二个4年期间，存活率从17%（6名婴儿中的1名）提高到了43%（14名婴儿中的6名）。围产期强化护理、感染预防以及高危婴儿母亲的早期转运改善了预后情况。从长期来看，7名幸存者中，1名有精神运动发育迟缓，1名患有癫痫，另外5名神经功能正常。这些儿童的身高和体重增长在2岁之前一直低于-2标准差水平，此后开始追赶。头围增长从2岁起增加到高于-2标准差的值。通过围产期强化护理，体重低于750克婴儿的预后情况正在改善，有望取得良好效果。
