Kitilla Tadesse
Brass MCH Hospital, P.O. Box 8588, Addis Ababa, Ethiopia.
Ethiop Med J. 2010 Oct;48(4):267-75.
Internal genital occlusion, mainly the fallopian tubes, secondary to pelvic inflammatory disease, is the most common causes of female infertility in sub-Saharan Africa and hysterosalpingography is a common diagnostic modality.
This was to discuss the findings of HSG and compare among primary and secondary infertility.
All infertility clinical records of five years (2001-2005) at FGAE central clinic were retrieved and those women who had undergone HSG procedure selected. The type and duration of infertility, socio-demographic factors and the recorded results of HSG were analyzed.
Among the total of 8582 attendants of the infertility clinic, 96% were women and 4% males. HSG was undertaken on 1716 (21%) women. Secondary and primary infertility were 894 (53%) and 804 (47%) respectively. Addis Ababa residents were 84%; married 93%; house wives 61% and office workers were 25%. About 39% (n = 662) of the women came to the clinic for investigation after 30 years of age and 42% (n = 714) after five years duration of infertility. There were 55% (n = 934) with secondary and above level of education while 10% had no formal school. Normal HSG was 604 (36%); significantly more in primary than secondary (p = 0.0002). The uterine cavity was normal in 1253 (73%) of which 21% had bilateral tubal blockage while among the abnormal, 44% showed bilateral block (P = 0.0000000). Tubal abnormalities were significantly associated with the acquired uterine defects than that of the 2.8% congenital uterine abnormalities. Of the 847 (49%) bilateral tubal patency, 14% had luminal defects. Unilaterally patent tubes were demonstrated in 324 (19%) women: more in secondary type (p = 0.0001) without significant difference between the right and the left. Bilateral tubal obstructions were noted in 527 (31%) of which 25% were symmetrical and 6% asymmetrical. Of the blocked tubes, the sites were 60% terminal and 37% proximal.
The review showed that most of the HSG were abnormal commonly tubal blockage: significantly more in secondary than primary infertility. End block was the commonest site and is associated with hydrosalpinx. The association of acquired uterine and tubal defects and secondary infertility is indicative of damage of internal genital tract following the previous pregnancies. Though applicable also to the primary infertility group, other infections (STI, TB) may contribute to the damage.
继发于盆腔炎的内生殖器阻塞,主要是输卵管阻塞,是撒哈拉以南非洲女性不孕最常见的原因,子宫输卵管造影是一种常用的诊断方法。
探讨子宫输卵管造影的结果,并比较原发性不孕和继发性不孕的情况。
检索了FGAE中心诊所五年(2001 - 2005年)的所有不孕临床记录,并选取了接受子宫输卵管造影检查的女性。分析不孕的类型和持续时间、社会人口统计学因素以及子宫输卵管造影的记录结果。
在不孕诊所的8582名就诊者中,96%为女性,4%为男性。1716名(21%)女性接受了子宫输卵管造影检查。继发性不孕和原发性不孕分别为894例(53%)和804例(47%)。亚的斯亚贝巴居民占84%;已婚者占93%;家庭主妇占61%,上班族占25%。约39%(n = 662)的女性在30岁以后前来诊所检查,42%(n = 714)在不孕持续五年后前来检查。55%(n = 934)的女性接受过中等及以上教育,10%未接受过正规学校教育。子宫输卵管造影正常的有604例(36%);原发性不孕中正常的比例显著高于继发性不孕(p = 0.0002)。1253例(73%)子宫腔正常,其中21%双侧输卵管阻塞,而在子宫腔异常的患者中,44%显示双侧阻塞(P = 0.0000000)。输卵管异常与后天性子宫缺陷的相关性显著高于2.8%的先天性子宫异常。在847例(49%)双侧输卵管通畅的患者中,14%有管腔缺陷。324例(19%)女性显示单侧输卵管通畅:继发性不孕类型中更多见(p = 0.0001),左右侧之间无显著差异。527例(31%)发现双侧输卵管阻塞,其中25%为对称性阻塞,6%为不对称性阻塞。在阻塞的输卵管中,阻塞部位60%在末端,37%在近端。
该综述表明,大多数子宫输卵管造影结果异常,常见为输卵管阻塞:继发性不孕中异常的比例显著高于原发性不孕。末端阻塞是最常见的部位,且与输卵管积水有关。后天性子宫和输卵管缺陷与继发性不孕的关联表明既往妊娠后内生殖道受到了损伤。虽然其他感染(性传播感染、结核病)也可能导致原发性不孕组的损伤,但上述情况同样适用。