甲状腺激素对胎鼠肠道培养物中乳糖酶活性的影响。
The effect of thyroid hormone on the activities of lactase in the culture of fetal rat intestine.
作者信息
Shimizu K, Nose O, Okada S
机构信息
Department of Pediatrics, Osaka Medical School, Japan.
出版信息
Cell Biol Int Rep. 1990 Dec;14(12):1143-8. doi: 10.1016/0309-1651(90)90023-r.
PMID:2128046
Abstract
The effects of thyroid hormone on lactase activities were studied in vitro organ culture of fetal rat intestine. Triiodothyronine inhibited lactase activities regardless the presence of dexamethasone. Also triiodothyronine decreased lactase activities when added after dexamethasone increased lactase activities. Our results suggest that thyroid hormone may have a role in the maturational changes of lactase activities during weaning.
摘要
在胎鼠肠道的体外器官培养中研究了甲状腺激素对乳糖酶活性的影响。无论是否存在地塞米松，三碘甲状腺原氨酸均抑制乳糖酶活性。当地塞米松增加乳糖酶活性后再添加三碘甲状腺原氨酸，其也会降低乳糖酶活性。我们的结果表明，甲状腺激素可能在断奶期间乳糖酶活性的成熟变化中起作用。
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