Sahota R S, Uddin F J, Al-Shukri J, Moir A A
Department of Otorhinolaryngology, Leicester Royal Infirmary, UK.
J Laryngol Otol. 2011 Apr;125(4):402-4. doi: 10.1017/S0022215110003014. Epub 2011 Jan 31.
Laryngeal papillomatosis is characterised by multiple papillomata affecting the upper respiratory tract. This condition is difficult to treat due to its recurrent nature. Treatment often involves surgical debulking. A number of non-surgical treatments have been reported. Intralesional cidofovir, a cytosine nucleoside analogue with antiviral activity, has been used in an attempt to manage the condition. We present a novel technique of administering cidofovir in a case of recurrent laryngotracheal papillomata.
喉乳头状瘤病的特征是上呼吸道出现多个乳头状瘤。由于其复发性，这种病症难以治疗。治疗通常包括手术切除。已经报道了多种非手术治疗方法。西多福韦，一种具有抗病毒活性的胞嘧啶核苷类似物，已被用于尝试治疗这种病症。我们介绍了一种在复发性喉气管乳头状瘤病例中施用西多福韦的新技术。
