Newcastle Neonatal Service, Royal Victoria Infirmary, Tyne, UK.
Arch Dis Child Fetal Neonatal Ed. 2011 Sep;96(5):F339-42. doi: 10.1136/adc.2010.191437. Epub 2011 Jan 31.
To establish a reference range for oxygen saturation (SpO(2)) in well preterm infants to guide home oxygen therapy using a pulse oximeter and Pulse Oximetry Data Analysis Software (PODS).
SpO(2) and heart-rate profiles of healthy preterm infants receiving mechanical ventilation for less than 6 h and supplemental oxygen for less than 48 h were monitored using a pulse oximeter. The stored data were downloaded from the monitor to a personal computer as individual files. Each infant's files of SpO(2) were subsequently displayed in graphic form, and a reference range was constructed using dedicated software, PODS.
43 infants were studied. The median value of all infants mean SpO(2) values was 95% (range 92-99%). The median duration of saturations less than 85% and between 85% and 90 % were 1% and 2% respectively. Using the study group median, 5th and 95th percentiles, a cumulative frequency curve of time against SpO(2) value was constructed (representing the reference range of SpO(2) profiles in healthy preterm infants).
The SpO(2) reference range can be used as an easy and practical guide to compare SpO(2) profiles of infants on home oxygen therapy and guide their oxygen therapy.
建立一个足月小样儿氧饱和度（SpO₂）的参考范围，以便使用脉搏血氧仪和脉搏血氧仪数据分析软件（PODS）指导家庭氧疗。
使用脉搏血氧仪监测接受机械通气时间少于 6 小时且补充氧气时间少于 48 小时的健康早产儿的 SpO₂和心率曲线。将存储的数据从监护仪下载到个人计算机上作为单个文件。随后将每个婴儿的 SpO₂文件以图形形式显示，并使用专用软件 PODS 构建参考范围。
共研究了 43 名婴儿。所有婴儿平均 SpO₂值的中位数为 95%（范围为 92-99%）。饱和度低于 85%和 85%至 90%的中位数持续时间分别为 1%和 2%。使用研究组中位数、第 5 百分位数和第 95 百分位数，构建了时间与 SpO₂值的累积频率曲线（代表健康早产儿 SpO₂曲线的参考范围）。
SpO₂参考范围可作为比较家庭氧疗婴儿 SpO₂曲线的简便实用指南，并指导其氧疗。
