Kamlin C Omar F, O'Donnell Colm P F, Davis Peter G, Morley Colin J
Division of Newborn Services, Royal Women's Hospital, Melbourne, Australia.
J Pediatr. 2006 May;148(5):585-9. doi: 10.1016/j.jpeds.2005.12.050.
Because the optimal concentration of oxygen (FiO2) required for stabilization of the newly born infant has not been established, the FiO2 is commonly adjusted according to the infant's oxygen saturation (SpO2). We aimed to determine the range of pre-ductal SpO2 in the first minutes of life in healthy newborn infants.
We applied an oximetry sensor to the infant's right palm or wrist of term and preterm deliveries immediately after birth. Infants who received any resuscitation or supplemental oxygen were excluded. SpO2 was recorded at 60 second intervals for at least 5 minutes and until the SpO2 was >90%.
A total of 205 deliveries were monitored; 30 infants were excluded from the study. SpO2 readings were obtained within 60 seconds of age from 92 of 175 infants (53%). The median (interquartile range) SpO2 at 1 minute was 63% (53%-68%). There was a gradual rise in SpO2 with time, with a median SpO2 at 5 minutes of 90% (79%-91%).
Many newborns have an SpO2 <90% during the first 5 minutes of life. This should be considered when choosing SpO2 targets for infants treated with supplemental oxygen in the delivery room.
由于尚未确定新生儿稳定所需的最佳氧浓度（FiO2），FiO2通常根据婴儿的血氧饱和度（SpO2）进行调整。我们旨在确定健康新生儿出生后最初几分钟内导管前SpO2的范围。
出生后立即将血氧饱和度测定传感器应用于足月儿和早产儿的右手掌或手腕。接受任何复苏或补充氧气的婴儿被排除在外。每隔60秒记录一次SpO2，至少记录5分钟，直到SpO2>90%。
共监测了205例分娩；30例婴儿被排除在研究之外。175例婴儿中有92例（53%）在出生后60秒内获得了SpO2读数。1分钟时SpO2的中位数（四分位间距）为63%（53%-68%）。SpO2随时间逐渐上升，5分钟时SpO2的中位数为90%（79%-91%）。
许多新生儿在出生后的前5分钟内SpO2<90%。在为产房接受补充氧气治疗的婴儿选择SpO2目标时应考虑这一点。
