Pelzer V, Von Ditfurth M, Wendel U
Universitäts-Frauenklinik Düsseldorf.
Geburtshilfe Frauenheilkd. 1990 Dec;50(12):964-8. doi: 10.1055/s-2008-1026400.
True precocious puberty represents a serious developmental disorder necessitating immediate therapeutic measures, whereas premature thelarche is a harmless variation from the norm. For the differential diagnosis the ultrasonographic evaluation of the internal genitalia is of value. Girls with precocious puberty reveal a statistically significantly greater uterus length and volume as well as ovarian size. The stimulated LH/FSH quotient allows verification of the diagnosis. This value is found always to be greater than 1 in precocious puberty and always less than 1 in premature thelarche.
真性性早熟是一种严重的发育障碍,需要立即采取治疗措施,而乳房过早发育是一种无害的正常变异。对于鉴别诊断,内生殖器的超声评估具有重要价值。性早熟女孩的子宫长度、体积以及卵巢大小在统计学上显著更大。促黄体生成素/促卵泡生成素比值可用于确诊。在性早熟中该值总是大于1,而在乳房过早发育中总是小于1。