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小儿腹腔镜胆囊切除术中的胆管损伤:全国性视角

Bile duct injuries during pediatric laparoscopic cholecystectomy: a national perspective.

作者信息

Raval Mehul V, Lautz Timothy B, Browne Marybeth

机构信息

Division of Research and Optimal Patient Care, American College of Surgeons, Chicago, Illinois, USA.

出版信息

J Laparoendosc Adv Surg Tech A. 2011 Mar;21(2):113-8. doi: 10.1089/lap.2010.0425. Epub 2011 Feb 1.

Abstract

BACKGROUND

Though rare, bile duct injuries (BDI) during laparoscopic cholecystectomy (LC) represent a major potential complication with significant associated morbidity. The objectives of this study were to (1) assess the national use of LC and incidence of BDI over time in the pediatric surgical population, (2) measure the added resource utilization burden associated with BDI, and (3) identify patient and hospital factors associated with BDI.

METHODS

All patients 0 to 20 years of age undergoing cholecystectomy were identified in the Kids' Inpatients Database from 1997 to 2006. National rates of LC use and BDI as well as overall costs were assessed using weighted estimates. Factors associated with BDI were analyzed with a logistic regression model.

RESULTS

Of 31,653 patients undergoing cholecystectomy, 28,243 (89.2%) underwent LC. Over time, the proportion of LC has risen from 81% in 1997 to 91% in 2006 (P < .001). Of patients undergoing LC, 0.44% had BDI with no significant change of BDI rate over time. Length of stay was 6.1 days for patients with BDI compared to 3.3 days for those without injury (P < .001). BDI patients had median costs of US $9550 as compared to US $6030 for non-BDI patients (P < .001). After taking patient, hospital, and disease-specific factors into consideration, BDI was more common in patients 5 years of age or less, nonwhite patients, and in patients admitted under an elective setting (all P < .01).

CONCLUSIONS

With increasing LC use, BDI remains a rare yet resource intense complication in children. Age, race, and admission related factors are associated with BDI and may provide guidance toward improving outcomes.

摘要

背景

尽管罕见,但腹腔镜胆囊切除术(LC)期间的胆管损伤(BDI)是一种主要的潜在并发症,伴有显著的相关发病率。本研究的目的是:(1)评估儿科手术人群中LC的全国使用情况以及BDI随时间的发病率;(2)衡量与BDI相关的额外资源利用负担;(3)确定与BDI相关的患者和医院因素。

方法

在1997年至2006年的儿童住院患者数据库中识别所有接受胆囊切除术的0至20岁患者。使用加权估计评估LC使用、BDI的全国发生率以及总体成本。使用逻辑回归模型分析与BDI相关的因素。

结果

在31653例接受胆囊切除术的患者中,28243例(89.2%)接受了LC。随着时间的推移,LC的比例从1997年的81%上升至2006年的91%(P < 0.001)。在接受LC的患者中,0.44%发生了BDI,BDI发生率随时间无显著变化。BDI患者的住院时间为6.1天,而未受伤患者为3.3天(P < 0.001)。BDI患者的中位成本为9550美元,而非BDI患者为6030美元(P < 0.001)。在考虑患者、医院和疾病特异性因素后,BDI在5岁及以下患者、非白人患者以及择期入院患者中更为常见(所有P < 0.01)。

结论

随着LC使用的增加,BDI在儿童中仍然是一种罕见但资源密集型的并发症。年龄、种族和入院相关因素与BDI相关,可能为改善结局提供指导。

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