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未来骶神经刺激的适应证。

Future indications for sacral nerve stimulation.

机构信息

Basingstoke and North Hampshire Hospital, Basingstoke, UK.

出版信息

Colorectal Dis. 2011 Mar;13 Suppl 2:23-8. doi: 10.1111/j.1463-1318.2010.02522.x.

Abstract

AIM

The aim of this article was to determine the effect of sacral nerve stimulation (SNS) on the treatment of faecal incontinence, constipation, irritable bowel syndrome, mixed urinary and bowel disorders, spinal injury and neurodegenerative disease, pain syndromes, and sexual dysfunction.

METHOD

A Medline search was performed including the keywords and/or MeSH headings of 'sacral nerve stimulation', 'neuromodulation', 'artificial pacemaker', 'faecal incontinence', 'constipation' and 'anal pain'. Further studies were identified by cross-referencing from relevant articles and by appraisal of recent peer-reviewed conference abstracts and proceedings.

RESULTS

SNS has been used for the treatment of urinary, bowel and sexual dysfunction, as well as pain resulting from such disorders, and dysfunction arising from nerve injury and degenerative disease. There is a paucity of high quality evidence to support the use of SNS for the majority of novel indications at present.

CONCLUSION

Good quality prospective, cross-over studies are required to determine the true benefits of SNS. Further research into patient selection, operative technique and stimulation parameters for existing indications will ensure a place for SNS in the future treatment algorithm of functional pelvic floor disorders.

摘要

目的

本文旨在确定骶神经刺激(SNS)对治疗粪便失禁、便秘、肠易激综合征、混合性尿便障碍、脊髓损伤和神经退行性疾病、疼痛综合征以及性功能障碍的效果。

方法

通过使用“骶神经刺激”、“神经调节”、“人工起搏器”、“粪便失禁”、“便秘”和“肛门疼痛”等关键词和/或 MeSH 标题进行 Medline 检索。通过交叉引用相关文章,并评估最近同行评议的会议摘要和会议记录,确定了其他研究。

结果

SNS 已被用于治疗尿便功能障碍和性功能障碍,以及由此类疾病引起的疼痛,以及由神经损伤和退行性疾病引起的功能障碍。目前,大多数新适应证的 SNS 应用缺乏高质量证据支持。

结论

需要进行高质量的前瞻性、交叉研究来确定 SNS 的真正益处。对现有适应证的患者选择、手术技术和刺激参数进行进一步研究,将确保 SNS 在未来功能性盆底障碍治疗算法中占有一席之地。

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