Department of Surgery, University Erlangen, Erlangen, Germany.
Colorectal Dis. 2011 Mar;13 Suppl 2:10-4. doi: 10.1111/j.1463-1318.2010.02519.x.
Indications for sacral nerve stimulation (SNS) for faecal incontinence have expanded over the last decade. This report aims to determine the clinical outcome of the current use of SNS in the treatment of faecal incontinence. Its objective is also to review the most recent role of SNS in patients with anal sphincter lesions.
The literature was searched using Medline and Cochrane databases. The search was restricted to publications in English. For the analysis, studies with <25 patients were excluded. For SNS in patients with sphincter defects, all papers were included.
Thirteen publications on the clinical outcome of SNS were included. Nine papers were identified reporting the application of SNS in patients with a morphological sphincter lesion. The most common outcome measures of clinical efficacy were frequency of incontinence using the Cleveland Clinic Incontinence Score. All studies demonstrated highly improved function across all outcome measures and improvement was statistically significant in all. Outcomes remain stable at long-term follow up. In patients with sphincteric gaps ranging from 17 to 180°, SNS was clinically effective at short-term follow up. The size of the gap appears to have no impact on outcome.
SNS has evolved to become a clinical efficient therapy applicable across a wide spectrum of causes of faecal incontinence with reproducible results. SNS can be considered to be an essential part of the current surgical treatment algorithm for faecal incontinence.
在过去的十年中,骶神经刺激(SNS)治疗粪便失禁的适应证不断扩大。本报告旨在确定目前 SNS 治疗粪便失禁的临床效果,并回顾 SNS 在肛门括约肌损伤患者中的最新作用。
使用 Medline 和 Cochrane 数据库检索文献。检索仅限于英文出版物。对于分析,排除了 <25 例患者的研究。对于有括约肌缺陷的 SNS 患者,所有论文均包括在内。
共纳入了 13 篇关于 SNS 临床效果的出版物。有 9 篇论文报道了 SNS 在形态学括约肌损伤患者中的应用。最常见的临床疗效评估指标是克利夫兰诊所失禁评分的失禁频率。所有研究均表明所有评估指标的功能均得到了显著改善,且在统计学上均具有显著性。长期随访结果稳定。对于括约肌间隙为 17 至 180°的患者,SNS 在短期随访时具有临床疗效。间隙大小似乎对结果没有影响。
SNS 已发展成为一种广泛适用于各种粪便失禁病因的有效临床治疗方法,具有可重复的效果。SNS 可被视为当前粪便失禁治疗算法中的重要组成部分。