Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center, Jeonju, Korea.
Korean J Anesthesiol. 2010 Dec;59 Suppl(Suppl):S114-8. doi: 10.4097/kjae.2010.59.S.S114. Epub 2010 Dec 31.
Long QT syndrome (LQTS) is an arrhythmogenic cardiovascular disorder resulting from mutations in cardiac ion channels. LQTS is characterized by prolonged ventricular repolarization and frequently manifests itself as QT interval prolongation on the electrocardiogram (ECG). A variety of commonly prescribed anesthetic drugs possess the adverse property of prolonging cardiac repolarization and may provoke serious ventricular tachyarrhythmia called 'torsades de pointes', ventricular fibrillation, and sudden death. We experienced a case of ventricular tachycardia and ventricular fibrillation after anesthetic induction and it came out into the open that anesthetic induction provoked long QT syndrome.
长 QT 综合征(LQTS)是一种由心脏离子通道基因突变引起的心律失常性心血管疾病。LQTS 的特征是心室复极延长,常表现为心电图(ECG)上 QT 间期延长。许多常用的麻醉药物具有延长心脏复极的不良特性,可能引发严重的室性心动过速,称为尖端扭转型室性心动过速、心室颤动和猝死。我们曾遇到一例麻醉诱导后出现室性心动过速和心室颤动的病例,结果发现麻醉诱导引发了长 QT 综合征。