Department of Anesthesiology and Pain Medicine, College of Medicine, CHA University, Seongnam, Korea.
Korean J Anesthesiol. 2010 Dec;59 Suppl(Suppl):S167-71. doi: 10.4097/kjae.2010.59.S.S167. Epub 2010 Dec 31.
Toxic epidermal necrolysis (TEN) is rare but serious cutaneous reaction with significant mortality and long-term morbidity. Various etiologies, particularly numerous medications and infectious agents have been implicated. It is characterized as inflammatory bullous lesions of the skin and mucous membrane and can develop serious complications such as pneumonia, pneumothorax, sepsis and renal failure. In general, patients with TEN are managed as severe second-degree burn patients with preventing excessive fluid deficit and infections. In this case, we aimed to present anesthetic management of a 26-year-old pregnant woman with TEN who received general anesthesia during emergent cesarean section.
中毒性表皮坏死松解症（TEN）是一种罕见但严重的皮肤反应，具有显著的死亡率和长期发病率。多种病因，特别是许多药物和感染因子都与 TEN 相关。TEN 的特征是皮肤和黏膜出现炎症性大疱性病变，并可能发生严重并发症，如肺炎、气胸、败血症和肾衰竭。一般来说，TEN 患者的治疗方法与严重二度烧伤患者相似，需要预防过度液体缺失和感染。在这种情况下，我们旨在介绍一例 TEN 孕妇行急诊剖宫产时接受全身麻醉的麻醉管理。
