Department of Pediatrics, Shizuoka City Shimizu Hospital, Shizuoka, Japan.
J Infect Chemother. 2011 Aug;17(4):559-62. doi: 10.1007/s10156-011-0213-6. Epub 2011 Feb 1.
Nontypeable Haemophilus influenzae (NTHi) commonly colonizes the upper respiratory tract of children and causes otitis media, sinusitis, and bronchitis. Invasive NTHi diseases such as meningitis and septicemia have rarely been reported, especially in children with underlying predisposing conditions such as head trauma and immune compromise. However, we report a previously healthy 2-year-old girl who developed meningitis and septicemia caused by NTHi biotype ΙΙΙ. She was treated with dexamethasone, meropenem, and ceftriaxone, and recovered uneventfully. We wish to emphasize that NTHi should be borne in mind as a potential pathogen that can cause meningitis and septicemia, even in previously healthy children.
无乳链球菌(NTHi)常定植于儿童上呼吸道,引起中耳炎、鼻窦炎和支气管炎。侵袭性 NTHi 疾病如脑膜炎和败血症则罕见报道,尤其是在存在潜在诱发因素如头部创伤和免疫抑制的儿童中。然而,我们报告了一例先前健康的 2 岁女孩,她因 NTHi 生物型 Ⅲ引起脑膜炎和败血症。她接受了地塞米松、美罗培南和头孢曲松治疗,并且恢复顺利。我们希望强调,即使是在先前健康的儿童中,NTHi 也应被视为一种可能引起脑膜炎和败血症的潜在病原体。