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[40至59岁男性血浆中激素质量变化及缺血性心脏病风险因素]

[Changes in the quality of hormones in blood plasma and ischemic heart disease risk factors in 40--59-year-old men].

作者信息

Gerasimova E N, Glazunov I S, Bodrova E A, Suchkova S N, Zykova V P

出版信息

Vopr Med Khim. 1978 Sep-Oct;24(5):657-66.

PMID:212869
Abstract

Testosterone, estradiol, hydrocortisone, total cholesterol, triglycerides, cholesterol of alpha-lipoproteins (alpha-CS) were estimated in blood plasma of 124 40--59 years old men examined in the course of an epidemyolodical study (representative selection). Content of insulin was estimated in 112 persons and of growth hormone--in 102 persons. Disbalance of steroid hormones (decrease in alpha-CS) was observed in men with one factor of risk of heart ischemic impairment. Occurrence of two factors of risk of heart ischemic impairment--hypertriglyceridemia and decrease in alpha-CS--was related not only to disbalance of steroid hormones but also to alteration in the ratio of protein hormones--insulin and growth hormone.

摘要

在一项流行病学研究(代表性抽样)过程中,对124名40 - 59岁男性的血浆进行了睾酮、雌二醇、氢化可的松、总胆固醇、甘油三酯、α-脂蛋白胆固醇(α-CS)的检测。对112人检测了胰岛素含量,对102人检测了生长激素含量。在有心脏缺血性损伤风险因素之一的男性中观察到类固醇激素失衡(α-CS降低)。心脏缺血性损伤的两个风险因素——高甘油三酯血症和α-CS降低——的出现不仅与类固醇激素失衡有关,还与蛋白质激素——胰岛素和生长激素比例的改变有关。

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