Zhang Gao-Qin, Wang Mei, Zhang Da-Ming, Liu Yao
Chinese People's Public Security University, Beijing 100038, China.
Fa Yi Xue Za Zhi. 2010 Oct;26(5):374-80.
Metabolomics is a new study, which use chromatography, mass spectrometry, nuclear magnetic resonance (NMR), capillary electrophoresis (CE) techniques on the cells, organs and other body fluids and metabolites in samples were isolated, purified and testing, re-use bioinformatics tools on the obtained data are analyzed to obtain one or a set of biomarker information. Based on analysis of the literatures in recent years, metabolomics was summarized from history, concept, advantage, methods, application, difficulties and challenges, journals and books, websites, and its application in forensic medicine was forecasted. As a new branch of global system biology, metabonomics developed rapidly, and its perspective on forensic medicine was feasible and very optimistic.
代谢组学是一项新的研究，它利用色谱法、质谱法、核磁共振（NMR）、毛细管电泳（CE）技术对细胞、器官及其他体液中的样本进行分离、纯化和检测，再利用生物信息学工具对获得的数据进行分析，从而获取一种或一组生物标志物信息。通过对近年来文献的分析，从代谢组学的历史、概念、优势、方法、应用、困难与挑战、期刊与书籍、网站等方面进行了综述，并对其在法医学中的应用进行了展望。作为全球系统生物学的一个新分支，代谢组学发展迅速，其在法医学中的前景是可行且非常乐观的。
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