LaMonica Gene E, Seifert Steven A, Rayburn William F
Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA.
J Reprod Med. 2010 Nov-Dec;55(11-12):520-2.
To determine the number of rattlesnake bites in pregnant women reported to U.S. poison centers and evaluate whether differences in management, treatments, or outcomes exist between pregnant and non-pregnant female bite victims.
Review was conducted of the database of the American Association of Poison Control Centers (AAPCC). Exposures coded as rattlesnake bites between 2001 and 2007 were included for all reproductive-age women (15-45 years).
Sixty-one poison control centers reported a total of 8,413 rattlesnake bites, with 767 (9.1%) involving reproductive-age women. Of these, 11 (1.4%) were pregnant. There were no significant differences between pregnant and nonpregnant victims with regard to rates of hospital admission, antivenom administration, or overall outcome codes. There were no adverse reactions to antivenom in pregnant women and no maternal deaths or fetal losses while in the hospital or during the period of poison center follow-up.
This rare condition is associated with favorable short-term pregnancy outcomes in the AAPCC database. In the absence of definitive evidence, we recommend standard management, including antivenom when indicated and extended fetal monitoring.
确定向美国中毒控制中心报告的孕妇被响尾蛇咬伤的数量，并评估怀孕和未怀孕的女性咬伤受害者在处理、治疗或结果方面是否存在差异。
对美国中毒控制中心协会（AAPCC）的数据库进行了回顾。纳入了2001年至2007年间所有育龄妇女（15 - 45岁）中编码为响尾蛇咬伤的暴露情况。
61个中毒控制中心报告了总共8413例响尾蛇咬伤事件，其中767例（9.1%）涉及育龄妇女。在这些病例中，11例（1.4%）为孕妇。在住院率、抗蛇毒血清使用情况或总体结果编码方面，怀孕和未怀孕的受害者之间没有显著差异。孕妇对抗蛇毒血清没有不良反应，在住院期间或中毒控制中心随访期间没有孕产妇死亡或胎儿丢失情况。
在AAPCC数据库中，这种罕见情况与良好的短期妊娠结局相关。在缺乏确凿证据的情况下，我们建议采用标准处理方法，包括在有指征时使用抗蛇毒血清并延长胎儿监测。
