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普通人群中脑膜炎奈瑟菌的鼻咽部携带情况与脑膜炎球菌病

Nasopharyngeal carriage of Neisseria meningitidis in general population and meningococcal disease.

作者信息

Ichhpujani R L, Mohan R, Grover S S, Joshi P R, Kumari S

机构信息

Department of Microbiology, N.I.C.D., Delhi.

出版信息

J Commun Dis. 1990 Dec;22(4):264-8.

PMID:2129123
Abstract

Nasopharyngeal carriage of Neisseria meningitidis was determined in the normal healthy population in Delhi at monthly intervals for a period of 2 years from January, 1986 to December, 1987. Of a total of 6513 individuals screened only 107 (1.64 per cent) were found to carry Neisseria meningitidis serogroup A. There was no age and sex difference in carriage. During the same period, data of laboratory confirmed cases of meningitis due to N. meningitidis serogroup A was obtained from 6 hospitals of Delhi which acted as sentinel centres. Of the total 11,870 pyogenic C.S.F. samples processed, only 557 (4.69 per cent) were due to N. meningitidis serogroup A. There was no correlation observed between the nasopharyngeal meningococcal carriage in the healthy population with the disease prevalence. There was no seasonal variation in nasopharyngeal carriage though upsurge in the number of meningococcal meningitis cases was noticed from January to April.

摘要

1986年1月至1987年12月的两年间,每月对德里正常健康人群进行一次脑膜炎奈瑟菌鼻咽部带菌情况的测定。在总共筛查的6513人中,仅107人(1.64%)被发现携带A群脑膜炎奈瑟菌。带菌情况不存在年龄和性别差异。同一时期,从德里作为哨点中心的6家医院获取了A群脑膜炎奈瑟菌所致脑膜炎实验室确诊病例的数据。在总共处理的11870份化脓性脑脊液样本中,仅557份(4.69%)由A群脑膜炎奈瑟菌引起。未观察到健康人群鼻咽部脑膜炎球菌带菌情况与疾病患病率之间存在相关性。鼻咽部带菌情况没有季节性变化,不过从1月至4月观察到脑膜炎球菌性脑膜炎病例数有所上升。

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