Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada.
Emerg Infect Dis. 2011 Feb;17(2):271-4. doi: 10.3201/eid1702.100629.
Near full-length genomes of 4 unclassified HIV-1 variants infecting patients enrolled in an antenatal cohort in Canada were obtained by sequencing. All 4 variants showed original recombination profiles, including A1/A2/J, A1/D, and A1/G/J/CRF11_cpx structures. Identification of these variants highlights the growing prevalence of unique recombinant forms of HIV-1 in North America.
通过测序获得了在加拿大一个产前队列中感染的 4 种未分类 HIV-1 变异体的近乎全长基因组。所有 4 种变异体均显示出原始的重组特征,包括 A1/A2/J、A1/D 和 A1/G/J/CRF11_cpx 结构。这些变异体的鉴定突出表明,在北美独特的 HIV-1 重组形式的流行率正在增加。