Disodium cromoglycate inhibits immunoglobulin production in vitro without affecting cell growth in human B cell lines.
作者信息
Kimata H, Yoshida A, Ishioka C, Mikawa H
机构信息
Department of Pediatrics, Kyoto University Hospital, Japan.
出版信息
Int Arch Allergy Appl Immunol. 1990;93(2-3):280-1. doi: 10.1159/000235314.
PMID:2129166
Abstract
The effect of disodium cromoglycate (DSCG) on human B cell lines (IM-9, GM-1056, and AF-10) was studied. DSCG inhibited immunoglobulin production by these B cell lines without affecting thymidine uptake or cell number. Thus, in addition to its antiallergic function, DSCG may also act as a B cell-modulating reagent in vitro.
摘要
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