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持续性腹水可以通过腹膜静脉分流术有效地治疗。

Persistent ascites can be effectively treated by peritoneovenous shunts.

机构信息

Great Ormond Street Hospital and UCL Institute of Child Health, London WC1N 3JH, United Kingdom.

出版信息

J Pediatr Surg. 2011 Feb;46(2):315-9. doi: 10.1016/j.jpedsurg.2010.11.006.

Abstract

AIM

The aim the study was to review our experience and determine the effectiveness of peritoneovenous shunts in the management of persistent ascites.

METHODS

A retrospective review of all patients who had a peritoneovenous shunt inserted for persistent ascites in our institution over 32 years (1977-2010) was performed.

RESULTS

Thirty-one peritoneovenous shunts were inserted into 25 patients. Records from 22 were available. Median age was 34 months (range, 1 month-12 years), with median duration of ascites of 1.75 months (range, 3 weeks-2.5 years). Sixteen had previous abdominal surgery, whereas one had previous thoracic surgery. Other underlying pathologies included hepatitis (n = 2), lymphohistiocytosis, lymphatic hypoplasia, and carcinomatosis. One was regarded as idiopathic. Previous management consisted of paracentesis (n = 15), dietary modification (n = 11), diuretics (n = 9), and total parenteral nutrition (TPN) (n = 4). One underwent fetal drainage of ascites. No intraoperative complications occurred. Eight (36%) had postoperative complications, including shunt occlusion (n = 2), pulmonary edema (n = 2), infection (n = 2), and wound leakage (n = 1). One developed a varix following shunt removal. The ascites resolved after shunting in 20 (91%) of the 22 children. Four died from their underlying pathology. In children with malignancy, the shunt allowed prompt resumption in treatment schedule.

CONCLUSION

This represents the largest series of children receiving peritoneovenous shunt for persistent ascites. It is a safe and effective treatment which should be considered early.

摘要

目的

本研究旨在回顾我们的经验,并确定持续性腹水患者采用腹膜静脉分流术治疗的效果。

方法

回顾性分析了我们医院 32 年来(1977 年至 2010 年)所有因持续性腹水而接受腹膜静脉分流术的患者。

结果

25 例患者共置入 31 个腹膜静脉分流管,其中 22 例患者的记录可查。患者中位年龄为 34 个月(1 个月至 12 岁),腹水持续时间中位数为 1.75 个月(3 周至 2.5 年)。16 例患者既往有腹部手术史,1 例患者有胸外科手术史。其他潜在的病理包括肝炎(2 例)、组织细胞增生症、淋巴管发育不良和癌性腹水。1 例被认为是特发性的。既往的治疗包括腹腔穿刺术(15 例)、饮食调整(11 例)、利尿剂(9 例)和全胃肠外营养(4 例)。1 例接受胎儿腹水引流术。无术中并发症。8 例(36%)发生术后并发症,包括分流管阻塞(2 例)、肺水肿(2 例)、感染(2 例)和伤口漏(1 例)。1 例在分流管移除后出现静脉曲张。22 例患儿中,20 例(91%)在分流后腹水消退。4 例患儿因基础疾病死亡。在患有恶性肿瘤的患儿中,分流术可使患儿及时恢复治疗计划。

结论

这是接受腹膜静脉分流术治疗持续性腹水的最大儿童系列研究。它是一种安全有效的治疗方法,应尽早考虑。

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