Urology and Nephrology Center, Urology Department, Mansoura University, Egypt.
Maturitas. 2011 Apr;68(4):374-7. doi: 10.1016/j.maturitas.2011.01.005. Epub 2011 Feb 2.
To assess differences between patients suffering from severe degree of stress urinary incontinence versus those with mild degree and to detect the risk factors of severity.
118 patients suffered from pure SUI were enrolled in a prospective study. According to VLPP, patients were categorized into 2 groups: mild (VLPP>60) and severe (VLPP<60). Risk factors included age, parity, gravidity, menopausal status, co-morbidities and surgical history were investigated.
35 patients had severe SUI; their mean VLPP±SD was 47±8cm H2O, while in 83 patients with mild SUI, mean VLPP was 90±20cm H2O. No significant difference was detected between both groups concerning clinical parameters except for the presence of bronchial asthma in which the difference was approaching statistical significance (P=0.07). Patients with multiple deliveries have triple risk to develop severe SUI. Obese patients with BMI>30 and those with bronchial asthma are more prone to develop severe type (OR: 1.9, 95%CI: .07-5 and OR: 9.4, 95% CI: 0.7-25 respectively).
Bronchial asthma, obesity and multiple parities might be associated with low VLPP. Severe SUI is a resultant of multi-factors rather than one risk factor.
评估重度压力性尿失禁患者与轻度患者之间的差异，并确定严重程度的相关危险因素。
对 118 例单纯性压力性尿失禁患者进行前瞻性研究。根据最大尿道压力（VLPP），将患者分为两组：轻度（VLPP＞60cmH2O）和重度（VLPP＜60cmH2O）。研究了包括年龄、产次、孕次、绝经状态、合并症和手术史在内的危险因素。
35 例患者患有重度压力性尿失禁，其平均 VLPP±SD 为 47±8cmH2O，而 83 例轻度压力性尿失禁患者的平均 VLPP 为 90±20cmH2O。除了支气管哮喘在两组之间存在差异接近统计学意义（P=0.07）外，两组间的临床参数无显著差异。多胎分娩的患者发生重度压力性尿失禁的风险增加三倍。BMI＞30 的肥胖患者和患有支气管哮喘的患者更容易发生重度压力性尿失禁（OR：1.9，95%CI：0.07-5；OR：9.4，95%CI：0.7-25）。
支气管哮喘、肥胖和多胎分娩可能与低 VLPP 相关。重度压力性尿失禁是多种因素共同作用的结果，而非单一危险因素所致。
