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放射性核素导向隐匿性病灶定位术同期切除同侧触诊阴性多发性乳腺病变

Simultaneous excision of ipsilateral nonpalpable multiple breast lesions using radioguided occult lesion localization.

机构信息

Department of General Surgery, Istanbul University Cerrahpasa Medical School, Istanbul, Turkey.

出版信息

Breast. 2011 Jun;20(3):241-5. doi: 10.1016/j.breast.2011.01.008. Epub 2011 Feb 2.

DOI:10.1016/j.breast.2011.01.008
PMID:21292486
Abstract

The purpose of this study was to determine the feasibility and effectiveness of ROLL technique for the identification and excision of ipsilateral nonpalpable multiple breast lesions. Between August 2005 and August 2010, eight women, aged 40-61 years, with a radiographic evidence of two separate nonpalpable lesions within the same breast underwent ROLL, as we termed it, double-ROLL. Each lesion was localized with Tc-99m-labeled human serum albumin macroaggregate under ultrasonography or mamography control. A gamma probe was used to guide surgical excisions. There was no radiotracer overlapping or extravasation in any case. Out of the 16 resected specimens, histopathologic examination revealed benign findings in 13 lesions and malignancy in 3. There was no lesion involvement at the surgical margins, and no residuals were detected in any of the benign cases during follow-up. Double-ROLL technique is feasible and safe for the identification and excision of such multiple ipsilateral breast lesions.

摘要

本研究旨在确定 ROLL 技术在同侧触诊阴性多发性乳腺病变的识别和切除中的可行性和有效性。2005 年 8 月至 2010 年 8 月期间,8 名年龄 40-61 岁的女性,乳腺影像学检查提示同一乳房内存在两个独立的触诊阴性病变,接受了我们所谓的双 ROLL 手术。每个病变均在超声或乳腺 X 线摄影控制下用 Tc-99m 标记的人血清白蛋白微球进行定位。使用伽马探针引导手术切除。在任何情况下均未发现放射性示踪剂重叠或外渗。在切除的 16 个标本中,组织病理学检查显示 13 个病变为良性,3 个为恶性。手术切缘无病变累及,且在随访的所有良性病例中均未发现残留。双 ROLL 技术是一种可行且安全的方法,可用于同侧触诊阴性多发性乳腺病变的识别和切除。

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引用本文的文献

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Radioguided localisation of impalpable breast lesions using 99m-Technetium macroaggregated albumin: Lessons learnt during introduction of a new technique to guide preoperative localisation.使用99m锝标记的大颗粒白蛋白对不可触及乳腺病变进行放射性引导定位:引入一种指导术前定位的新技术过程中的经验教训
J Med Radiat Sci. 2015 Mar;62(1):6-14. doi: 10.1002/jmrs.36. Epub 2013 Dec 25.