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[西班牙重症监护病房腹泻的患病率:一项多中心研究]

[Prevalence of diarrhea in critical patients units in Spain: a multicenter study].

作者信息

Izaguirre Guerricagoitia L, Truchuelo Aragón A

机构信息

Cuidados intensivos, Hospital Donostia, San Sebastián, Guipúzcoa, España.

出版信息

Enferm Intensiva. 2011 Apr-Jun;22(2):65-73. doi: 10.1016/j.enfi.2010.10.002. Epub 2011 Feb 2.

DOI:10.1016/j.enfi.2010.10.002
PMID:21292524
Abstract

INTRODUCTION

Diarrhea is a frequent complication in patients admitted to intensive care and nursing consumes a significant percentage of time for them. Although this is a common condition, the exact size of the problem is unknown. The main objective of this study has been to determine the prevalence of diarrhea in hospitalized patients in critical care units (CCU)in Spain.

METHOD

An observational, cross-sectional, prospective and multicenter study including the month of April 2008 on patients in CCUs. Variables recorded were age, gender, diagnosis, severity (Apache II, Sofa), stool frequency and consistency, skin condition, pressure ulcer risk scale according to Norton, average time for hygiene, mortality, associated treatments, diet, mortality. Statistical analysis method: SPSS 14.00.

RESULTS

Twenty-five critical care units, to which 2,114 patients were admitted, participated. 162 questionnaires corresponding to different diarrhea episodes of 141 patients were received. Mean prevalence was 6.4% (range 0.01%-30%). Age 59 ± 14.6 years, 56.7% men. Principal medical diagnoses: Patients with respiratory condition 36 (25.5%), patients with sepsis and multi-organ failure 26 (18.4%) postoperatory patients with varied etiology 21 (14.9%), subarachnoid hemorrhage 15 (10.6%), heart patients 13 (9.2%), polytraumatized patients 12 (8.5%), severe pancreatitis 10 (7.1%), autoimmune diseases 7 (5%) and others (0.7%). Apache II: 12.54 ± 9 (10). Admission Norton Scale: 9.38 ± 4 percent. Days of stay 15.9 ± 9.5, percentage of patients administered sedoanalgesia: 61.7% (we calculated the percentage of each medical treatment over the 162 episodes registered) (some patients received more than one medication simultaneously): morphine (25.5%), benzodiazepines (34.84%), propofol (33.3%), remifentanil (17%), inotropos (38.3%), antibiotics (93.2%), antifungals (41.3%), laxatives (21.6%), selective digestive decontamination (30.2%), enteral nutrition (67.3%), parenteral (24.1%), oral (24.7%). Average frequency of stools per day was 5.3. Consistency was liquid slurry in 59.3% and 40.7% of cases. 4.9% of patients had positive culture for Clostridium difficile. The skin condition was unchanged in 61.7% of cases, stage I lesions (17.9%), stage II lesion (13.6%), stage III lesion (3.7%) and stage IV (2.5%). Average time used for hygiene performed with the diarrhea was 2h 45. Average staff involved was 14 nurses, 14 auxiliaries and 9 guards. To control diarrhea, medication was used (9.9%), pot (1.2%), diapers and absorbent pads (98.1%), fecal collection device (10.5%) and rectal probes (9.3%).

CONCLUSIONS

This study has allowed us to determine the prevalence of diarrhea in patients in critical care units. We were able to describe the characteristics of these patients and to establish the presence of skin lesions, the time spent by staff to handle this problem as well as materials used for management.

摘要

引言

腹泻是重症监护患者常见的并发症,护理腹泻患者耗费了护理人员大量时间。尽管这是一种常见病症,但问题的实际严重程度尚不清楚。本研究的主要目的是确定西班牙重症监护病房(CCU)住院患者腹泻的患病率。

方法

一项观察性、横断面、前瞻性多中心研究,涵盖2008年4月CCU的患者。记录的变量包括年龄、性别、诊断、病情严重程度(急性生理与慢性健康状况评分系统II [Apache II]、序贯器官衰竭评估 [Sofa])、大便频率和性状、皮肤状况、根据诺顿量表评估的压疮风险、平均护理时间、死亡率、相关治疗、饮食、死亡率。统计分析方法:SPSS 14.00。

结果

25个重症监护病房参与研究,共收治2114例患者。收到141例患者不同腹泻发作对应的162份问卷。平均患病率为6.4%(范围0.01% - 30%)。年龄59 ± 14.6岁,男性占56.7%。主要医疗诊断:呼吸系统疾病患者36例(25.5%),脓毒症和多器官功能衰竭患者26例(18.4%),病因各异的术后患者21例(14.9%),蛛网膜下腔出血患者15例(10.6%),心脏病患者13例(9.2%),多发伤患者12例(8.5%),重症胰腺炎患者10例(7.1%),自身免疫性疾病患者7例(5%),其他患者(0.7%)。Apache II评分:12.54 ± 9(10)。入院时诺顿量表评分:9.38 ± 4分。住院天数15.9 ± 9.5天,接受镇静镇痛治疗的患者比例:61.7%(我们计算了162例记录病例中每种药物治疗的比例)(部分患者同时接受多种药物治疗):吗啡(25.5%)、苯二氮䓬类药物(34.84%)、丙泊酚(33.3%)、瑞芬太尼(17%)、血管活性药物(38.3%)、抗生素(93.2%)、抗真菌药物(41.3%)、泻药(21.6%)、选择性消化道去污(30.2%)、肠内营养(67.3%)、肠外营养(24.1%)、口服营养(24.7%)。每日平均大便次数为5.3次。59.3%的病例大便性状为稀便,40.7%为糊状便。4.9%的患者艰难梭菌培养呈阳性。61.7%的病例皮肤状况无变化,I期损伤(17.9%),II期损伤(13.6%),III期损伤(3.7%),IV期损伤(2.5%)。腹泻患者平均护理时间为2小时45分钟。平均参与护理的人员包括14名护士、14名辅助人员和9名护工。为控制腹泻,使用了药物(9.9%)、便盆(1.2%)、尿布和吸水垫(98.1%)、粪便收集装置(10.5%)和直肠探头(9.3%)。

结论

本研究使我们能够确定重症监护病房患者腹泻的患病率。我们能够描述这些患者的特征,确定皮肤损伤情况、工作人员处理该问题所花费的时间以及用于管理的材料。

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