Institut de Recherche pour le Développement, Unité Mixte de Recherche 216, Paris, France.
Am J Trop Med Hyg. 2011 Feb;84(2):267-9. doi: 10.4269/ajtmh.2011.10-0139.
The question of malaria in the postpartum period is controversial. Malaria was investigated during a randomized trial of intermittent preventive treatment in pregnancy in Benin. Women infected at delivery were tested for parasitemia in the early postpartum period; they had not received treatment unless they were symptomatic. Among the 35 of 1,346 infected women, parasitologic follow-up results could not be interpreted in 15 because they were treated for symptoms, 18 cleared parasitemia spontaneously within five days postpartum, and 2 had a strong decrease in parasitemia before being treated. Because the placenta is the privileged site for sequestration of parasites, it facilitates their persistence during pregnancy, and its elimination may rapidly induce their clearance.
产后疟疾问题存在争议。在贝宁进行的妊娠期间间歇性预防治疗随机试验中对疟疾进行了研究。分娩时感染的妇女在产后早期进行了寄生虫血症检测；除非有症状，否则她们不会接受治疗。在 1346 名感染妇女中的 35 名中，由于症状治疗，15 名妇女的寄生虫学随访结果无法解释，18 名妇女在产后五天内寄生虫血症自然清除，2 名妇女在接受治疗前寄生虫血症急剧减少。由于胎盘是寄生虫隔离的特权部位，这有助于它们在怀孕期间的持续存在，而胎盘的清除可能会迅速诱导它们的清除。
