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意大利的糖尿病与肾脏替代治疗:患病率、主要特征及并发症

Diabetes mellitus and renal replacement therapy in Italy: prevalence, main characteristics and complications.

作者信息

Catalano C, Postorino M, Kelly P J, Fabrizi F, Enia G, Goodship T H, Fulcher G R, Maggiore Q

机构信息

Associazione Nazionale Emodializzati (ANED), Centro di Fisiologia Clinica del Consiglio Nazionale delle Ricerche, Reggio Calabria, Italy.

出版信息

Nephrol Dial Transplant. 1990;5(9):788-96. doi: 10.1093/ndt/5.9.788.

Abstract

A number of reports on dialysis and transplantation for diabetic patients in the UK and USA are available. The aim of the present survey was to assess the prevalence, main characteristics and complications of diabetic patients treated by dialysis and transplantation in Italy. On 31 December 1987 in Italy, 1605 diabetic patients were being treated by dialysis or transplantation. The prevalence was 28 per million compared with the UK and the USA where the corresponding figures were 17 and 78 per million respectively. The annual incidence in 1987 was 9 per million (UK: 4 per million; USA: 33 per million). The mean age of the Italian diabetic patients was 59 years whereas that for British diabetic patients similarly evaluated was 48 years. Of the Italian diabetic patients 67% had NIDDM (UK: 22%; USA: 50%). Haemodialysis was used in 81% of the Italian patients, peritoneal dialysis in 14%, and only 5% were transplanted. This is in contrast to the UK where only 18% of the patients were treated by haemodialysis and 39% were transplanted. Amongst Italian patients who started RRT in 1987, 9% died within the year, and of the remainder 38% had severe bilateral visual impairment (UK 35%), 3% had had amputations (UK 6%), 7% had suffered from disabling strokes (UK 6%) and 7% had had a myocardial infarction (UK 17%). Before 31 December 1987 another 2.2% developed severe bilateral visual impairment, 0.6% underwent amputations, 1.0% had a disabling stroke and 0.6% suffered from a myocardial infarction. The proportion of diabetic patients treated by RRT in Italy is twice that of the UK but only half that of the USA.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

关于英国和美国糖尿病患者透析及移植治疗的报告有很多。本次调查的目的是评估意大利接受透析和移植治疗的糖尿病患者的患病率、主要特征及并发症。1987年12月31日,意大利有1605名糖尿病患者正在接受透析或移植治疗。其患病率为百万分之28,相比之下,英国和美国的相应数字分别为百万分之17和百万分之78。1987年的年发病率为百万分之9(英国:百万分之4;美国:百万分之33)。意大利糖尿病患者的平均年龄为59岁,而经类似评估的英国糖尿病患者平均年龄为48岁。意大利糖尿病患者中67%患有非胰岛素依赖型糖尿病(英国:22%;美国:50%)。81%的意大利患者采用血液透析,14%采用腹膜透析,仅5%接受了移植。这与英国形成对比,英国仅有18%的患者接受血液透析,39%接受了移植。在1987年开始接受肾脏替代治疗的意大利患者中,9%在当年死亡,其余患者中38%有严重双侧视力损害(英国为35%),3%接受了截肢手术(英国为6%),7%发生了致残性中风(英国为6%),7%发生了心肌梗死(英国为17%)。在1987年12月31日之前,另有2.2%出现严重双侧视力损害,0.6%接受了截肢手术,1.0%发生了致残性中风,0.6%发生了心肌梗死。意大利接受肾脏替代治疗的糖尿病患者比例是英国的两倍,但仅为美国的一半。(摘要截选至250词)

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