Studies on the localization and accessibility of sites in fibrin which are involved in the acceleration of the activation of plasminogen by tissue-type plasminogen activator.
作者信息
Nieuwenhuizen W, Schielen W J, Yonekawa O, Tesser G I, Voskuilen M
机构信息
Gaubius Institute TNO, Leiden, The Netherlands.
出版信息
Adv Exp Med Biol. 1990;281:83-91. doi: 10.1007/978-1-4615-3806-6_8.
PMID:2129380
Abstract
摘要
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Studies on the localization and accessibility of sites in fibrin which are involved in the acceleration of the activation of plasminogen by tissue-type plasminogen activator.关于纤维蛋白中与组织型纤溶酶原激活剂加速纤溶酶原激活相关位点的定位和可及性的研究。
Adv Exp Med Biol. 1990;281:83-91. doi: 10.1007/978-1-4615-3806-6_8.
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Sites in fibrin involved in the acceleration of plasminogen activation by t-PA. Possible role of fibrin polymerisation.纤维蛋白中参与组织型纤溶酶原激活物（t-PA）加速纤溶酶原激活的位点。纤维蛋白聚合的可能作用。
Thromb Res. 1994 Aug 1;75(3):343-7. doi: 10.1016/0049-3848(94)90248-8.
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Conversion of fibrinogen to fibrin: mechanism of exposure of tPA- and plasminogen-binding sites.纤维蛋白原向纤维蛋白的转化：组织型纤溶酶原激活物（tPA）和纤溶酶原结合位点暴露的机制
Biochemistry. 2000 Dec 26;39(51):15730-41. doi: 10.1021/bi001847a.
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Soluble fibrin degradation products potentiate tissue plasminogen activator-induced fibrinogen proteolysis.可溶性纤维蛋白降解产物增强组织型纤溶酶原激活物诱导的纤维蛋白原蛋白水解作用。
J Clin Invest. 1991 Mar;87(3):1082-90. doi: 10.1172/JCI115069.
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Comparison of the effects of fibrinogen and fibrin products and isolated peptide chains on the fibrin-mediated stimulation of plasminogen activation by tissue-type plasminogen activator, and on the fibrin-dependent enhancement of the amidolytic activity of one-chain tissue-type plasminogen activator.纤维蛋白原和纤维蛋白产物以及分离的肽链对纤维蛋白介导的组织型纤溶酶原激活物刺激纤溶酶原激活的影响，以及对单链组织型纤溶酶原激活物酰胺水解活性的纤维蛋白依赖性增强作用的比较。
Biol Chem Hoppe Seyler. 1990 Nov;371(11):1067-75. doi: 10.1515/bchm3.1990.371.2.1067.
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Making tissue-type plasminogen activator more fibrin specific.使组织型纤溶酶原激活剂对纤维蛋白更具特异性。
Protein Eng. 1993 Jul;6(5):529-34. doi: 10.1093/protein/6.5.529.
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Fibrin-mediated plasminogen activation.纤维蛋白介导的纤溶酶原激活。
Ann N Y Acad Sci. 2001;936:237-46. doi: 10.1111/j.1749-6632.2001.tb03512.x.
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Functional characterization of monoclonal antibodies directed against fibrin binding domains of tissue-type plasminogen activator.针对组织型纤溶酶原激活剂纤维蛋白结合结构域的单克隆抗体的功能特性分析
J Biol Chem. 1989 May 15;264(14):7957-61.
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[PC-12 cells hydrolyze the fibrin clot by producing both plasminogen and its tissue activator].[PC-12细胞通过产生纤溶酶原及其组织激活剂来水解纤维蛋白凝块]。
Ukr Biokhim Zh (1999). 2004 Mar-Apr;76(2):64-8.
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