Chiner E, Arbona C, Pérez D, Escrig V, García-Conde J, Marín J
Servicios de Neumología y Hematología, Hospital Clínico Universitario, Valencia.
An Med Interna. 1990 Jun;7(6):304-6.
2 cases of mycetomas are presented as exceptional manifestations of invasive aspergillosis. Both patients had diagnosis of leukemia and neutropenia, secondary to chemotherapy. The clinical features were subacute and mainly fever, cough, dyspnea and multiple infiltrates with cavitations and balls of hyphae within cysts shown in chest x-ray. The precipitin tests were positive for A. fumigatus and A. flavus, and were correlated with the specimens of the bronchial brushing. One of the patients improved with antimycotics and normalization of neutropenia.
本文报告2例足菌肿作为侵袭性曲霉病的特殊表现。两名患者均诊断为继发于化疗的白血病和中性粒细胞减少症。临床特征为亚急性,主要表现为发热、咳嗽、呼吸困难,胸部X线显示多发浸润影,伴有空洞形成及囊肿内的菌丝球。烟曲霉和黄曲霉沉淀素试验呈阳性,且与支气管刷检标本结果相关。其中1例患者经抗真菌药物治疗及中性粒细胞减少症恢复正常后病情好转。