Bilginer Burcak, Narin Firat, Oguz Kader Karli, Uzun Sennur, Soylemezoglu Figen, Akalan Nejat
Hacettepe University, School of Medicine, Department of Neurosurgery, Ankara, Turkey.
Turk Neurosurg. 2011 Jan;21(1):22-6.
Cerebellar astrocytomas are benign tumors of the central nervous system. They represent 10% of all pediatric intracranial brain tumors and 30% of all pediatric posterior fossa tumors especially in the first two decades of life.
We reviewed the medical records of patients; age at the time of surgery, pre- and post operative magnetic resonance imaging (MRI), localisation of the tumor, hydrocephalus, surgical approach, pre- and post operative neurological status, post operative adjuvant therapy and outcome were documented.
The male to female ratio was 20/11. Age at the time of evaluation ranged from 3 to 23 years. Age at the time of surgery ranged from 1 to 18 years. Follow-up duration after surgery was 1-12 years. 55% of these tumors were located at the cerebellar vermis and 45% were at the cerebellar hemispheres. Complete surgical resection was done in 74% of these patients. 5 patients had a second operation because of residual tumor. Ventriculoperitoneal shunt insertion was performed in 3 of 31 patients because of symptomatic hydrocephalus and 1 patient had an endoscopic third ventriculostomy pre-operatively. 90% of these patients had no neurological sequelae at follow-up evaluation.
Cerebellar astrocytomas are benign tumors where total resection is possible in the majority of cases with an excellent outcome.
小脑星形细胞瘤是中枢神经系统的良性肿瘤。它们占所有儿童颅内脑肿瘤的10%，占所有儿童后颅窝肿瘤的30%，尤其是在生命的前二十年。
我们回顾了患者的病历；记录了手术时的年龄、术前和术后的磁共振成像（MRI）、肿瘤的位置、脑积水情况、手术入路、术前和术后的神经状态、术后辅助治疗及结果。
男女比例为20/11。评估时的年龄范围为3至23岁。手术时的年龄范围为1至18岁。术后随访时间为1至12年。这些肿瘤中55%位于小脑蚓部，45%位于小脑半球。74%的患者进行了完整的手术切除。5例患者因肿瘤残留进行了二次手术。31例患者中有3例因症状性脑积水进行了脑室腹腔分流术，1例患者术前进行了内镜下第三脑室造瘘术。90%的患者在随访评估时无神经后遗症。
小脑星形细胞瘤是良性肿瘤，大多数情况下可以进行全切除，预后良好。
