Dr. Lütfi Kırdar Kartal Training and Research Hospital, Istanbul, Turkey.
Am J Ophthalmol. 2011 Apr;151(4):637-643.e1. doi: 10.1016/j.ajo.2010.10.029. Epub 2011 Feb 4.
To compare astigmatic keratotomy (AK) outcomes in high astigmatism after deep anterior lamellar keratoplasty (DALK) and after penetrating keratoplasty (PK) in keratoconus patients.
Prospective, comparative, interventional case series.
This study comprised 20 eyes that underwent DALK and 24 eyes that underwent PK. After suture removal, all eyes had more than 5 diopters (D) of astigmatism and underwent standard manual 1-pair, 90-degree, and 90% corneal thickness AK incisions. The main outcome measures included preoperative and postoperative manifest refraction, uncorrected visual acuity, best spectacle-corrected visual acuity, surgically induced astigmatism, Orbscan II (Bausch & Lomb) corneal topography results, keratometric astigmatism, and complications.
All eyes completed 6 months of follow-up. The overcorrection rate was 35% and 41.6% in the DALK and PK groups, respectively (P=.75). At 6 months after AK, logarithm of the minimal angle of resolution uncorrected visual acuity improved from 0.88 ± 0.20 to 0.54 ± 0.26 and from 1.0 ± 0.34 to 0.53 ± 0.26 in the DALK and PK groups, respectively (P=.01 to P<.01). Best spectacle-corrected visual acuity improved from 0.16 ± 0.09 to 0.13 ± 0.08 and from 0.16 ± 0.12 to 0.11 ± 0.08 in the DALK and PK groups, respectively (P=.13 to P=.01). The mean refractive cylinder was decreased 2.74 ± 1.44 D in the DALK group and 3.18 ± 2.96 D in the PK group (P=.35). Surgically induced astigmatism was 6.10 ± 3.27 D in the DALK group and 7.15 ± 2.98 D in the PK group (P=.36).
The manual AK for the treatment of postkeratoplasty astigmatism after DALK and PK in keratoconus patients is a safe and effective surgical procedure, allowing similar refractive cylinder reduction and improvement in uncorrected visual acuity and best spectacle-corrected visual acuity.
比较深板层角膜移植术(DALK)和穿透性角膜移植术后圆锥角膜患者高散光的角膜散光切开术(AK)结果。
前瞻性、对照、干预性病例系列。
本研究包括 20 只接受 DALK 的眼和 24 只接受 PK 的眼。缝线拆除后,所有眼均有超过 5 屈光度(D)的散光,并接受标准的手动 1 对、90 度和 90%角膜厚度 AK 切口。主要观察指标包括术前和术后的视力、未矫正视力、最佳矫正视力、手术诱导散光、Orbscan II(Bausch & Lomb)角膜地形图结果、角膜曲率散光和并发症。
所有眼均完成 6 个月随访。DALK 和 PK 组的过矫率分别为 35%和 41.6%(P=.75)。AK 后 6 个月,未矫正视力的最小分辨角对数提高至 0.54±0.26(DALK 组)和 0.53±0.26(PK 组),分别为 0.88±0.20(DALK 组)和 1.0±0.34(PK 组)(P=.01 至 P<.01)。最佳矫正视力从 0.16±0.09 提高至 0.13±0.08(DALK 组)和 0.16±0.12(PK 组)至 0.11±0.08(PK 组)(P=.13 至 P=.01)。DALK 组平均屈光度下降 2.74±1.44 D,PK 组下降 3.18±2.96 D(P=.35)。DALK 组手术诱导散光为 6.10±3.27 D,PK 组为 7.15±2.98 D(P=.36)。
对于圆锥角膜患者深板层角膜移植术后和穿透性角膜移植术后的后发性散光,手动 AK 是一种安全有效的手术方法,可实现相似的屈光度降低,并改善未矫正视力和最佳矫正视力。