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[皮肤科实践中复杂皮肤及软组织感染的经验性抗生素治疗]

[Empirical antibiotic therapy of complicated skin and soft tissue infections in dermatological practice].

作者信息

Magyar Andrea, Garaczi Edina, Hajdú Edit, Kemény Lajos

机构信息

Szegedi Tudományegyetem, Általános Orvostudományi Kar, Bőrgyógyászati és Allergológiai Klinika, Szeged.

出版信息

Orv Hetil. 2011 Feb 13;152(7):252-8. doi: 10.1556/OH.2011.28968.

DOI:10.1556/OH.2011.28968
PMID:21296734
Abstract

UNLABELLED

Erysipelas is an acute bacterial infection of the skin predominantly caused by Streptococcus pyogenes. According to the international classification complicated erysipelas belongs to the complicated skin and soft tissue infections. Complicated infections are defined as severe skin involvement or when the infection occurs in compromised hosts. These infections frequently involve Gram-negative bacilli and anaerobic bacteria.

AIMS

The aim of this study was to compare the efficacy of the empirical antibiotic therapy for the patients who were admitted to the Department of Dermatology and Allergology, University of Szeged.

METHODS

The empirical therapy was started according to a previously determined protocol. The data of 158 patients with complicated skin and soft tissue infections were analyzed and the microbiology culture specimens and the isolates were also examined.

RESULTS AND CONCLUSIONS

The results show that penicillin is the first choice for the treatment of erysipelas. However, the complicated skin and soft tissue infections require broad-spectrum antibiotics.

摘要

未标注

丹毒是一种主要由化脓性链球菌引起的皮肤急性细菌感染。根据国际分类,复杂性丹毒属于复杂性皮肤和软组织感染。复杂性感染被定义为严重的皮肤受累或感染发生在免疫功能低下的宿主身上。这些感染经常涉及革兰氏阴性杆菌和厌氧菌。

目的

本研究的目的是比较经验性抗生素治疗对塞格德大学皮肤病与变态反应科收治患者的疗效。

方法

根据先前确定的方案开始经验性治疗。分析了158例复杂性皮肤和软组织感染患者的数据,并对微生物培养标本和分离株进行了检查。

结果与结论

结果表明,青霉素是治疗丹毒的首选药物。然而,复杂性皮肤和软组织感染需要使用广谱抗生素。

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