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嗜酸性粒细胞性食管炎:一名HIV阳性患者吞咽困难的意外病因。

Eosinophilic oesophagitis: an unsuspected aetiology for dysphagia in an HIV-positive patient.

作者信息

Batog C, Psevdos G, Paniz-Mondolfi A, Srivastava S, Sharp V L

机构信息

Department of Medicine, St Luke's Roosevelt Hospital, New York, NY, USA.

出版信息

Int J STD AIDS. 2010 Dec;21(12):842-4. doi: 10.1258/ijsa.2010.010020.

DOI:10.1258/ijsa.2010.010020
PMID:21297098
Abstract

Patients with HIV/AIDS are often afflicted with oesophageal disorders. Opportunistic infections such as candidiasis, herpes simplex, cytomegalovirus, mycobacterial infections, Kaposi sarcoma or lymphoma involving the oesophagus, motility disorders and reflux oesophagitis are the usual culprits. Eosinophilic oesophagitis (EE), a recently recognized entity, is an important cause of dysphagia, food impaction and chest discomfort. We report the case of an HIV-infected man who had persistent dysphagia for six months despite treatment with proton pump inhibitor. He was diagnosed with EE after having endoscopic evaluation and biopsy of his oesophagus and was successfully treated with swallowed fluticasone. This case represents the first reported case of EE in an HIV-infected individual.

摘要

艾滋病病毒/艾滋病患者常患有食管疾病。机会性感染,如念珠菌病、单纯疱疹、巨细胞病毒、分枝杆菌感染、累及食管的卡波西肉瘤或淋巴瘤、动力障碍和反流性食管炎是常见病因。嗜酸性粒细胞性食管炎(EE)是一种最近才被认识的疾病,是吞咽困难、食物嵌塞和胸部不适的重要原因。我们报告一例艾滋病病毒感染男性病例,尽管使用质子泵抑制剂治疗,但仍持续吞咽困难6个月。经食管内镜评估和活检后,他被诊断为嗜酸性粒细胞性食管炎,通过吞咽氟替卡松成功治愈。该病例是首例报道的艾滋病病毒感染个体患嗜酸性粒细胞性食管炎的病例。

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