1,2,4-三唑-3-甲酰胺向利巴韦林-5'-磷酸的酶促转化及其与所提出的作用机制的关系。 - Suppr

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超能文献

The enzymic conversion of 1,2,4-triazole-3-carboxamide to ribavirin-5'-phosphate and its relationship to the proposed mechanism of action.

作者信息

Streeter D G, Miller J P, Robins R K, Simon L N

出版信息

Ann N Y Acad Sci. 1977 Mar 4;284:201-10. doi: 10.1111/j.1749-6632.1977.tb21952.x.

DOI:10.1111/j.1749-6632.1977.tb21952.x

PMID:212973

Abstract

摘要

相似文献

The enzymic conversion of 1,2,4-triazole-3-carboxamide to ribavirin-5'-phosphate and its relationship to the proposed mechanism of action.1,2,4-三唑-3-甲酰胺向利巴韦林-5'-磷酸的酶促转化及其与所提出的作用机制的关系。

Ann N Y Acad Sci. 1977 Mar 4;284:201-10. doi: 10.1111/j.1749-6632.1977.tb21952.x.

Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line.腺苷激酶在一种培养的人类细胞系中启动了利巴韦林激活的主要途径。

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Synthesis and biochemical evaluation of nucleosides of naphthoquinone heterocycles.

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Synthesis and biological activity of certain 1,2,3-triazole carboxamide nucleosides related to bredinin and pyrazofurin.与布累迪宁和吡唑呋林相关的某些1,2,3-三唑甲酰胺核苷的合成及生物活性

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Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.马铃薯（Solanum tuberosum L.）块茎圆盘内嘌呤生物合成、补救途径及降解的概况

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Recycling of alpha-D-ribose 1-phosphate for nucleoside interconversion.α-D-核糖1-磷酸的循环利用用于核苷相互转化。

Biochim Biophys Acta. 1997 Apr 17;1335(1-2):6-22.

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent.新型广谱抗病毒药物1-β-D-呋喃核糖基-1,2,4-三唑-3-甲酰胺（病毒唑）的作用机制

Proc Natl Acad Sci U S A. 1973 Apr;70(4):1174-8. doi: 10.1073/pnas.70.4.1174.

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Thermophilic phosphoribosyltransferases HB27 in nucleotide synthesis.

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Phosphorylation of ribavirin and viramidine by adenosine kinase and cytosolic 5'-nucleotidase II: Implications for ribavirin metabolism in erythrocytes.利巴韦林和病毒唑核苷经腺苷激酶和胞质5'-核苷酸酶II磷酸化：对红细胞中利巴韦林代谢的影响。

Antimicrob Agents Chemother. 2005 Jun;49(6):2164-71. doi: 10.1128/AAC.49.6.2164-2171.2005.

Plasma disappearance, urine excretion, and tissue distribution of ribavirin in rats and rhesus monkeys.利巴韦林在大鼠和恒河猴体内的血浆清除、尿液排泄及组织分布

Antimicrob Agents Chemother. 1981 Jun;19(6):1042-9. doi: 10.1128/AAC.19.6.1042.

Broad-spectrum synergistic antiviral activity of selenazofurin and ribavirin.硒唑呋林与利巴韦林的广谱协同抗病毒活性。

Antimicrob Agents Chemother. 1984 Oct;26(4):466-75. doi: 10.1128/AAC.26.4.466.

Ribavirin and inosiplex: a review of their present status in viral diseases.利巴韦林与肌苷：它们在病毒性疾病中的现状综述

Drugs. 1981 Aug;22(2):111-28. doi: 10.2165/00003495-198122020-00002.

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