Stanford University School of Medicine, Falk Cardiovascular Research Center, Palo Alto, California, USA.
Curr Opin Cardiol. 2011 Mar;26(2):123-31. doi: 10.1097/HCO.0b013e3283437485.
Ventricular reserve is emerging a strong predictor of outcome in heart failure and cardiovascular disease. Ventricular reserve is the term used to describe the extent of increase or change in ventricular function that occurs during exercise or pharmacological stress (typically with dobutamine).
The interest in ventricular reserve lies in its ability to assess viability in coronary artery disease, to predict clinical outcome and response to therapy in patients with heart failure and to screen patients for early cardiovascular disease.
In this paper, we will review the emerging role of ventricular reserve in heart failure and pulmonary hypertension. We will also explore the mechanisms involved in the pathophysiology of impaired ventricular reserve and discuss future directions of research in the field.
心室储备是心力衰竭和心血管疾病预后的一个强有力的预测指标。心室储备是一个术语，用于描述在运动或药物刺激（通常使用多巴酚丁胺）期间心室功能增加或变化的程度。
对心室储备的兴趣在于其评估冠心病患者的存活能力、预测心力衰竭患者的临床预后和治疗反应以及筛查早期心血管疾病患者的能力。
本文综述了心室储备在心力衰竭和肺动脉高压中的新作用。我们还将探讨心室储备受损的病理生理学中的相关机制，并讨论该领域的未来研究方向。
