Yakut Mustafa, Kabaçam Gökhan, Öztürk Ayşegül, Soykan Irfan
Department of Gastroenterology, University of Ankara, Ankara, Turkey.
South Med J. 2011 Mar;104(3):179-84. doi: 10.1097/SMJ.0b013e31820c018c.
Cameron lesions are located at the neck of large hiatal hernias, and are associated with anemia or overt gastrointestinal (GI) bleeding. The aim of this study was to investigate the clinical and endoscopic properties of patients with Cameron lesions.
Eighteen patients were diagnosed as having large hiatal hernia and Cameron lesions. Patients with Cameron lesions (n = 18) were compared to patients with large hiatal hernias without Cameron lesions (n = 26), by means of presenting symptoms and endoscopic findings.
The mean age of patients with Cameron lesions was significantly higher than patients without Cameron lesions (71.1 ± 11.63 vs 56.7 ± 17.4 years, P = 0.005). The ratio of female patients with Cameron lesions was higher compared to patients with large hiatal hernia without Cameron lesions (14/18 [77.7%] vs 12/26 [46.1%], P = 0.00). While 12 of 18 patients with Cameron lesions had overt GI bleeding, none of the patients with large hiatal hernia without Cameron lesions had signs of GI bleeding. Fifteen of 18 patients had ulcers in the hernia sac and the others had linear erosions. There was no significant difference between patients with and without Cameron lesions by means of hemoglobin levels (11.1 ± 2.20 vs 12.2 ± 2.5 g/dL, P = 0.157).
Most patients with large hiatal hernia and Cameron lesions presented with overt GI bleeding. Patients with Cameron lesions tend to be older females. In patients with anemia and GI bleeding, large hiatal hernia and Cameron erosions should also be considered.
卡梅伦病变位于大型食管裂孔疝的颈部，与贫血或明显的胃肠道（GI）出血相关。本研究的目的是调查患有卡梅伦病变患者的临床和内镜特征。
18例患者被诊断为患有大型食管裂孔疝和卡梅伦病变。通过呈现的症状和内镜检查结果，将患有卡梅伦病变的患者（n = 18）与没有卡梅伦病变的大型食管裂孔疝患者（n = 26）进行比较。
患有卡梅伦病变的患者的平均年龄显著高于没有卡梅伦病变的患者（71.1±11.63岁对56.7±17.4岁，P = 0.005）。与没有卡梅伦病变的大型食管裂孔疝患者相比，患有卡梅伦病变的女性患者比例更高（14/18 [77.7%]对12/26 [46.1%]，P = 0.00）。18例患有卡梅伦病变的患者中有12例出现明显的胃肠道出血，而没有卡梅伦病变的大型食管裂孔疝患者均没有胃肠道出血迹象。18例患者中有15例在疝囊中有溃疡，其他患者有线性糜烂。通过血红蛋白水平比较，有和没有卡梅伦病变的患者之间没有显著差异（11.1±2.20对12.2±2.5 g/dL，P = 0.157）。
大多数患有大型食管裂孔疝和卡梅伦病变的患者出现明显的胃肠道出血。患有卡梅伦病变的患者往往是老年女性。对于贫血和胃肠道出血的患者，也应考虑大型食管裂孔疝和卡梅伦糜烂。
