Department of Gynaecology Oncology, Royal Hobart Hospital, Hobart, Tasmania, Australia.
Int J Gynecol Cancer. 2010 Oct;20(7):1256-8. doi: 10.1111/IGC.0b013e3181ecb562.
Pyomyositis is a rare complication of chemotherapy that is commonly seen in tropical climates and in patients with immunodeficiency states. Owing to its rarity and subacute presentation, its diagnosis is often delayed. It has been reported after intense chemotherapy for hematological cancers. We present a case of a 58-year-old woman with endometrial cancer who developed pyomyositis after the first cycle of carboplatin and paclitaxel with no prior predisposing factor except for cancer and premedication with corticosteroids. The patient improved once the diagnosis was established and managed with antibiotics and drainage of abscess. Full recovery was made with a protracted course of antibiotics.Early diagnosis of this entity with appropriate investigations and treatment prevents septicemia, which can often be life threatening.
肌脓肿是一种罕见的化疗并发症，常见于热带地区和免疫功能低下的患者。由于其罕见性和亚急性表现，其诊断常常被延误。它曾在血液系统癌症的强烈化疗后被报道。我们报告了一例 58 岁女性子宫内膜癌患者，在接受卡铂和紫杉醇的第一个周期化疗后发生肌脓肿，除癌症外，无其他潜在诱发因素，且预先使用了皮质类固醇。一旦诊断成立，患者使用抗生素和脓肿引流进行治疗后病情得到改善。经过长时间的抗生素治疗，患者完全康复。早期诊断该疾病并进行适当的检查和治疗可预防败血症，败血症往往具有生命威胁。
