Suzuki Kenji, Kurono Yuichi, Kobayashi Toshimitsu, Nishimura Tadao, Baba Shunkichi, Harabuchi Yasuaki, Fujisawa Toshiyuki, Yamanaka Noboru, Ubukata Kimiko, Ikeda Fumiaki
Department of Otolaryngology, Second Hospital, Fujita Health University.
Jpn J Antibiot. 2010 Aug;63(4):312-8.
The minimum inhibitory concentrations (MICs) and the mutant prevention concentrations (MPCs) of garenoxacin (GRNX), were compared to those of levofloxacin (LVFX), and moxifloxacin (MFLX) against 78 Streptococcus pneumoniae isolates from otorhinolaryngological infections in Japan during the period January 2007 to June 2007. The MIC and MPC for 90% of the isolates (MIC90 and MPC90) of GRNX were 0.06 and 0.12 microg/mL, respectively, and were the lower values than LVFX and MFLX MIC90s and MPC90s. The ratios of MPC/MIC of GRNX were the lower values than those of LVFX and MFLX.
在2007年1月至2007年6月期间，比较了加替沙星（GRNX）与左氧氟沙星（LVFX）和莫西沙星（MFLX）对78株来自日本耳鼻咽喉感染患者的肺炎链球菌的最低抑菌浓度（MIC）和突变预防浓度（MPC）。GRNX对90%菌株的MIC和MPC（MIC90和MPC90）分别为0.06和0.12μg/mL，低于LVFX和MFLX的MIC90和MPC90值。GRNX的MPC/MIC比值低于LVFX和MFLX。
