Peel Trisha N, Buising Kirsty L, Choong Peter F M
Department of Surgery, University of Melbourne, St Vincent's Hospital Melbourne, Australia.
ANZ J Surg. 2011 Jan;81(1-2):32-9. doi: 10.1111/j.1445-2197.2010.05541.x. Epub 2010 Nov 10.
Arthroplasty for arthritis has led to remarkable improvement in patient quality of life and alleviation of symptoms. A major complication of this surgery is infection. This review examines current understanding of epidemiology, diagnosis, treatment and prevention of prosthetic joint infections. In particular, this article focuses on the role of biofilm formation in the pathogenesis of device infections and the diagnostic and treatment challenges associated with this process.
用于治疗关节炎的关节成形术显著改善了患者的生活质量并减轻了症状。该手术的一个主要并发症是感染。本综述探讨了目前对人工关节感染的流行病学、诊断、治疗和预防的认识。特别是,本文重点关注生物膜形成在器械感染发病机制中的作用以及与这一过程相关的诊断和治疗挑战。