Theegarten D, Anhenn O, Müller K-D
Institut für Pathologie und Neuropathologie, Universitätsklinikum Essen, Hufelandstr. 55, 45147, Essen, Deutschland.
Pathologe. 2011 Mar;32(2):159-64. doi: 10.1007/s00292-010-1404-0.
Infections play a crucial role in organ transplantations as possible complications. Viruses, bacteria, fungi and parasites are potential agents. The relevance of individual diseases depends on the organ transplanted. Morphology of the inflammatory reaction is given by the agent involved, but often several reactions can be caused by the same agent and different agents can also lead to the same reaction. Histology therefore provides concrete identification of the causal agent only in some cases, such that additional microbiological diagnostics are necessary. Results from these investigations should be transferred to the pathologist to distinguish between infection-associated changes and transplant rejection.
感染作为可能的并发症在器官移植中起着关键作用。病毒、细菌、真菌和寄生虫都是潜在的病原体。个别疾病的相关性取决于所移植的器官。炎症反应的形态取决于所涉及的病原体,但同一病原体通常可引发多种反应,不同病原体也可能导致相同的反应。因此,组织学仅在某些情况下能明确病原体,所以还需要进行额外的微生物学诊断。这些检查结果应传达给病理学家,以区分感染相关变化和移植排斥反应。